333786

Sigma-Aldrich

L-Dopa-(phenyl-d3)

≥98 atom % D, ≥98% (CP)

Synonym(s):
3-(3,4-Dihydroxyphenyl-2,5,6-d3)-L-alanine
Linear Formula:
(HO)2C6D3CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
200.21
MDL number:
PubChem Substance ID:
NACRES:
NA.12

Quality Level

isotopic purity

≥98 atom % D

assay

≥98% (CP)

optical activity

[α]27/D −11.5°, c = 5 in 1 M HCl

application(s)

mass spectrometry (MS): suitable

mp

292 °C (dec.) (lit.)

mass shift

M+3

storage temp.

2-8°C

SMILES string

[2H]c1c([2H])c(C[C@H](N)C(O)=O)c([2H])c(O)c1O

InChI

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1/i1D,2D,4D

InChI key

WTDRDQBEARUVNC-UOCCHMHCSA-N

Related Categories

Application

L-Dopa-(phenyl-d3) or (3-(3,4-dihydroxyphenyl-2,5,6-d3)-L-alanine) can be used as an internal standard for the quantification of methyldopa in human plasma by LC-MS-MS based method.

Packaging

1 g in glass bottle
250 mg in glass bottle
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

pictograms

Exclamation mark

signalword

Warning

hazcat

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Jeong-Ook Lee et al.
Journal of ginseng research, 42(3), 389-399 (2018-07-10)
The antioxidant effects of Panax ginseng have been reported in several articles; however, little is known about the antimelanogenesis effect, skin-protective effect, and cellular mechanism of Panax ginseng, especially of P. ginseng calyx. To understand how an ethanol extract of...
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Quantification of methyldopa in human plasma by high-performance liquid chromatography?electrospray tandem mass spectrometry: Application to a bioequivalence study
Oliveira CH, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 2(768), 341-348 (2002)
Glauber de S Araujo et al.
PloS one, 7(1), e29561-e29561 (2012-01-19)
Capsule production is common among bacterial species, but relatively rare in eukaryotic microorganisms. Members of the fungal Cryptococcus genus are known to produce capsules, which are major determinants of virulence in the highly pathogenic species Cryptococcus neoformans and Cryptococcus gattii....
Dario Breitel et al.
Metabolic engineering, 65, 185-196 (2020-11-27)
L-DOPA, also known as Levodopa or L-3,4-dihydroxyphenylalanine, is a non-standard amino acid, and the gold standard drug for the treatment for Parkinson's Disease (PD). Recently, a gene encoding the enzyme that is responsible for its synthesis, as a precursor of...

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