361399

Tetrabutylammonium fluoride solution

75 wt. % in H₂O

• Synonym(s): TBAF solution
• Linear Formula: [CH₃(CH₂)₃]₄NF
• CAS Number: 429-41-4
• Molecular Weight: 261.46
• Beilstein: 3762762
• MDL number: MFCD00011747
• PubChem Substance ID: 24862218
• NACRES: NA.22

Properties

• form: viscous liquid
• Quality Level: 100
• concentration: 75 wt. % in H₂O
• density: 0.953 g/mL at 25 °C
• SMILES string: [F-].CCCC[N+](CCCC)(CCCC)CCCC
• InChI: 1S/C16H36N.FH/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;/h5-16H2,1-4H3;1H/q+1;/p-1
• InChI key: FPGGTKZVZWFYPV-UHFFFAOYSA-M

Description

Application

Reactant for preparation of:

• Triple monoamine reuptake inhibitors as a new generation of antidepressants
• Alcohols via hydrolysis of alkyl silyl ethers neutral pH in mixed organic-aqueous buffered solutions
• Oligoribonucleotides with phosphonate-modified linkages
• Aryl alkyl alcohols via Nozaki-Hiyama allylation catalyzed by chiral bipyridyldiol ligands and chromium trichloride
• Conjugated dienoic acid esters using Suzuki coupling reactions
• Macrocyclic o-aminobenzamide Hsp90 inhibitorwith antitumor activity
• Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors
• Anti-diabetic polyacetylenic glucosides

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 - H315 - H319 - H361fd - H412
• Precautionary Statements: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2
• Supplementary Hazards: EUH032
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves