D-Glucose-¹³C₆

Name: <SC>D</SC>-Glucose-<SUP>13</SUP>C<SUB>6</SUB>
Brand: ALDRICH

≥99 atom % ¹³C, ≥99% (CP)

Synonym(s):

Labeled Glucose, D-Glucose-ul-¹³C, Dextrose-¹³C₆

Slide 1 of 6

Note: This product can be packaged on demand. For information on pricing, availability and packaging of custom sizes, please contact Stable Isotopes Customer Service

About This Item

Empirical Formula (Hill Notation):

¹³C₆H₁₂O₆

CAS Number:

110187-42-3

Molecular Weight:

186.11

NACRES:

NA.12

PubChem Substance ID:

24864278

UNSPSC Code:

12142200

MDL number:

MFCD00037544

Key Documents

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Product Name

D-Glucose-¹³C₆, ≥99 atom % ¹³C, ≥99% (CP)

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1

SMILES string

O[13CH2][13C@H]1O[13C@H](O)[13C@H](O)[13C@@H](O)[13C@@H]1O

InChI key

WQZGKKKJIJFFOK-NYKRWLDMSA-N

isotopic purity

≥99 atom % ¹³C

assay

≥99% (CP)

form

powder

optical activity

[α]25/D +52.0°, c = 2 in H₂O (trace NH₄OH)

technique(s)

bio NMR: suitable
protein expression: suitable
protein purification: suitable

mp

150-152 °C (lit.)

mass shift

M+6

Quality Level

200

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Show Differences

1 of 4

This Item	297046	552003	310808
Sigma-Aldrich 389374 D-Glucose-¹³C₆	Sigma-Aldrich 297046 D-Glucose-1-¹³C	Sigma-Aldrich 552003 D-Glucose-1,2,3,4,5,6,6-d₇	Sigma-Aldrich 310808 D-Glucose-6-¹³C
isotopic purity ≥99 atom % ¹³C	isotopic purity 99 atom % ¹³C	isotopic purity 97 atom % D	isotopic purity 99 atom % ¹³C
mass shift M+6	mass shift -	mass shift M+7	mass shift M+1
technique(s) bio NMR: suitable, protein purification: suitable, protein expression: suitable	technique(s) bio NMR: suitable	technique(s) bio NMR: suitable, protein expression: suitable	technique(s) -
assay ≥99% (CP)	assay 99% (CP)	assay 99% (CP)	assay 99% (CP)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder

Application

D-Glucose-¹³C₆ has been used:

for de novo fatty acid (FA) synthesis[1]
as a component in tracing media for the analysis of stable isotope tracer[2]
in minimal media for recombinant protein production[3]
for cell suspension[4]

Biochem/physiol Actions

D-Glucose-13C6 functions as a tracer and helps to access glucose kinetics in vivo.[5]

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Victor BMM, et al.

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Individual ionization constants of all the carboxyl groups in ribonuclease HI from Escherichia coli determined by NMR.

Y Oda et al.

Biochemistry, 33(17), 5275-5284 (1994-05-03)

All of the individual carboxyl groups (the side-chain carboxyl groups of Asp and Glu, and the C-terminal alpha-carboxyl group) in Escherichia coli ribonuclease HI, which is an enzyme that cleaves the RNA strand of a RNA/DNA hybrid, were pH-titrated, and

A convenient gram-scale synthesis of uridine diphospho(13C6)glucose.

Zoran Dinev et al.

Carbohydrate research, 341(10), 1743-1747 (2006-04-11)

A simple gram-scale synthesis of uridine diphospho(13C6)glucose is presented from D-(13C6)glucose. The critical step uses a 1H-tetrazole-catalyzed coupling of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl-1-phosphate and UMP-morpholidate. The uridine diphospho(13C6)glucose was used in the structural identification of (1-->3)-beta-D-glucan from Lolium multiflorum.

RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma

Houles T, et al.

Cancer Research, canres-ca2215 (2018)

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D-Glucose-13C6

≥99 atom % 13C, ≥99% (CP)