All Photos(4)



Polyethylenimine, branched

average Mw ~25,000 by LS, average Mn ~10,000 by GPC, branched

Linear Formula:
CAS Number:
MDL number:
PubChem Substance ID:


viscous liquid

mol wt

average Mn ~10,000 by GPC
average Mw ~25,000 by LS


≤1% water

refractive index

n20/D 1.5290


13,000-18,000(50 °C)


250 °C (lit.)


1.030 g/mL at 25 °C

SMILES string




InChI key


Looking for similar products? Visit Product Comparison Guide


Used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.
Detergents, adhesives, water treatment, printing inks, dyes, cosmetics, and paper industry, adhesion promoter, lamination primer, fixative agent, flocculant, cationic dispersant, stability enhancer, surface activator, chelating agent, scavenger for aldehydes and oxides.


100, 250 mL in poly bottle
1 L in poly bottle

Physical form

Branched polymer


Exclamation markEnvironment

Signal Word


Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids



Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the concentration and purity of Polyethylenimine, Product 408727?

    This product is the pure product of polyethyleneimine. At room temperature this product is a liquid and not a solid. The purity of this product is not routinely determined.

  4. At what temperature does Product 408727, Polyethylenimine, decompose?

    Polyethylenimine (mw ~25,000) begins to decompose at 225 °C.

  5. What is the solubility of Product 408727, Polyethylenimine?

    We do not test the solubility of this product.  However, according to our supplier, this product is miscible with water and ethylene glycol, and soluble in ethanol.

  6. What are the end groups on Product 408727, Polyethylenimine?

    The end groups are primary, secondary, and tertiary amines that are in a ratio of 1 : 1.2 : 0.76, respectively.

  7. What is the water content of Product 408727, Polyethylenimine?

    This product will contain less than 1% water. The lot specific value is reported on the Certificate of Analysis.

  8. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  9. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Hsuan-Wen Chiu et al.
Oncotarget, 8(55), 94129-94141 (2017-12-08)
The betanodavirus B2 protein targets the mitochondria and acts as a "death factor", but its effect on lung cancer cells is unknown. We examined the effect of the B2 protein on triggering apoptosis or necroptosis
Baoshun Lin et al.
Medicine, 94(31), e1301-e1301 (2015-08-08)
As an immunotoxin, diphtheria toxin has been widely used in gene therapy and gene function assays for its roles in protein synthesis inhibition, and the aim of our study is to set up a nonintegrating lentiviral system for specific expression
Yi-Hsuan Lee et al.
Acta biomaterialia, 63, 210-226 (2017-09-14)
The development of osteochondral tissue engineering is an important issue for the treatment of traumatic injury or aging associated joint disease. However, the different compositions and mechanical properties of cartilage and subchondral bone show the complexity of this tissue interface
Wei Dong et al.
Frontiers in immunology, 9, 2312-2312 (2018-10-26)
Sequential infection with antigenically distinct influenza viruses induces cross-protective immune responses against heterologous virus strains in animal models. Here we investigated whether sequential immunization with antigenically distinct influenza vaccines can also provide cross-protection. To this end, we compared immune responses
Rosa-Maria Ferraiuolo et al.
Oncotarget, 8(14), 23337-23352 (2017-04-21)
The Ras/Raf/MEK/ERK pathway conveys growth factor and mitogen signalling to control the phosphorylation of a plethora of substrates regulating proliferation, survival, and migration. The Ras signalling pathway is frequently associated with poor prognosis and drug resistance in various cancers including


Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

Related Content

Novel Inks for Direct-Write Assembly of 3-D Periodic Structures

New methods for materials fabrication at the micro- and nanoscale will drive scientific and technological advances in areas of materials science, chemistry, physics, and biology. The broad diversity of potentially relevant materials, length scales, and architectures underscores the need for flexible patterning approaches. One important example is the fabrication of 3D periodic structures composed of colloidal, polymeric, or semiconductor5 materials.

Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

Recent Progress on Nonviral Delivery Carriers for CRISPR/Cas9 Systems

The CRISPR/Cas9 system has recently emerged as a highly specific, efficient, and versatile gene editing technology that can be utilized to build disease models and correct diseased genes. Safe and effective delivery vectors for the CRISPR/Cas9 system are in critical need to enable clinical development and future applications of CRISPR/Cas9 systems. Professor Yang Liu summarizes recent progress in nonviral nanoparticle approaches for CRISPR/Cas9 delivery.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service