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Magnesium stearate

technical grade

Stearic acid magnesium salt
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:


technical grade

Quality Level


palmitate salt, 25%
stearate salt, 65%


200 °C (lit.)

SMILES string




InChI key


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General description

Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.


Magnesium stearate may be used as excipient in the formulations of diclofenac sodium tablets. It may be used for the preparation of tramadol HCl matrix tablets.


1 kg in poly drum
25 g in poly bottle

Storage Class Code

13 - Non Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Delay effect of magnesium stearate on tablet dissolution in acidic medium.
Ariyasu A, et al.
International Journal of Pharmaceutics, 511(2), 757-764 (2016)
Paola Bertocchi et al.
Journal of pharmaceutical and biomedical analysis, 37(4), 679-685 (2005-03-31)
The aim of this work was to compare the dissolution behaviour of six diclofenac sodium prolonged release tablets of different brands obtained from the national market. The formulations contain the same amount of drug substance but different types and/or amount
Effect of mixing time on the lubricating properties of magnesium stearate and the final characteristics of the compressed tablets.
Kikuta J-I and Kitamori N.
Drug Development and Industrial Pharmacy, 20(3), 343-355 (1994)
Louis St-Onge et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 8(2), 272-288 (2005-08-30)
Laser-induced breakdown spectroscopy (LIBS) was evaluated for its potential as a process analytical tool for the rapid determination of magnesium stearate (MgSt) distribution within and between tablets as well as between batches in a typical manufacturing run, and for the
Jaleh Varshosaz et al.
AAPS PharmSciTech, 7(1), E24-E24 (2006-04-06)
The objective of this work was to develop matrix sustained-release tablets of highly water-soluble tramadol HCl using natural gums (xanthan [X gum] and guar [G gum]) as cost-effective, nontoxic, easily available, and suitable hydrophilic matrix systems compared with the extensively

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