All Photos(1)

643440

Sigma-Aldrich

L-Arginine-13C6 hydrochloride

99 atom % 13C, 95% (CP)

Synonym(s):
SILAC Amino Acid, (S)-(+)-2-Amino-5-[(aminomethyl)amino]pentanoic acid-13C6 hydrochloride, 13C Labeled arginine, 13C Labeled arginine hydrochloride
Linear Formula:
H2N13C(NH)NH13CH2(13CH2)213CH(NH2)13CO2H · HCl
CAS Number:
Molecular Weight:
216.62
MDL number:
PubChem Substance ID:
NACRES:
NA.12

Quality Level

isotopic purity

99 atom % 13C

assay

95% (CP)

optical activity

[α]20/D +22°, c = 12 in 10% HCl

technique(s)

protein expression: suitable

mp

226-230 °C (dec.) (lit.)

mass shift

M+6

SMILES string

Cl[H].N[13C@@H]([13CH2][13CH2][13CH2]N[13C](N)=N)[13C](O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1/i1+1,2+1,3+1,4+1,5+1,6+1;

InChI key

KWTQSFXGGICVPE-BJPSCUOKSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Pulsed Stable Isotope labeling of amino acid has been used to study host-cell function, survival, the precise intracellular pathways in protein synthesis of HIV-1 infected human monocytederived macrophages. Identification of viral proteins from coronavirus infectious bronchitis-infected cells has been achieved with Stable Isotope labeling in conjunction with LC-MS/MS.

Packaging

100 mg in glass bottle
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Gino L Turra et al.
Microbiology spectrum, 9(2), e0080921-e0080921 (2021-09-30)
Import and oxidative folding of proteins in the mitochondrial intermembrane space differ among eukaryotic lineages. While opisthokonts such as yeast rely on the receptor and oxidoreductase Mia40 in combination with the Mia40:cytochrome c oxidoreductase Erv, kinetoplastid parasites and other Excavata/Discoba
Edward Emmott et al.
Molecular & cellular proteomics : MCP, 9(9), 1920-1936 (2010-05-15)
Virus-host interactions involve complex interplay between viral and host factors, rendering them an ideal target for proteomic analysis. Here we detail a high throughput quantitative proteomics analysis of Vero cells infected with the coronavirus infectious bronchitis virus (IBV), a positive
Zehan Hu et al.
Cell reports, 28(13), 3486-3496 (2019-09-26)
The target of rapamycin complex 1 (TORC1) is a master regulator of cell homeostasis, which promotes anabolic reactions and synchronously inhibits catabolic processes such as autophagy-mediated protein degradation. Its prime autophagy target is Atg13, a subunit of the Atg1 kinase
Koshi Imami et al.
Molecular cell, 72(1), 84-98 (2018-09-18)
Emerging evidence indicates that heterogeneity in ribosome composition can give rise to specialized functions. Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The effect of posttranslational modifications has not been studied systematically. Analyzing ribosome
Katrina Meyer et al.
Cell, 175(1), 239-253 (2018-09-11)
Many disease-causing missense mutations affect intrinsically disordered regions (IDRs) of proteins, but the molecular mechanism of their pathogenicity is enigmatic. Here, we employ a peptide-based proteomic screen to investigate the impact of mutations in IDRs on protein-protein interactions. We find

Related Content

Protein Structural Analysis

Protein structure provides valuable information that can be used to infer protein function. The study of protein structure and mapping of protein interactions, expression levels, and location enables the identification of disease biomarkers and potential drug targets for therapeutic treatment.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service