Merck
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779776

Sigma-Aldrich

Methyl-β-cyclodextrin

produced by Wacker Chemie AG, Burghausen, Germany, ≥95.0% cyclodextrin basis (calculated)

Synonym(s):
Cavasol W7 M, Methyl-beta-cyclodextrin
CAS Number:
NACRES:
NA.22

Quality Level

grade

produced by Wacker Chemie AG, Burghausen, Germany

assay

≥95.0% cyclodextrin basis (calculated)

form

powder

extent of labeling

1.6-1.9 molar substitution

impurities

≤0.2% unsubstituted cyclodextrin
≤0.2% volatile organics
≤2% chloride

loss

≤7.0% loss on drying

mp

180-182 °C (lit.)

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

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Application

Methyl-β-cyclodextrin (M-β-CD) can be used as a reactant to prepare ternary inclusion complex of diclofenac (DCF) in the presence of monoethanolamine (MEA). This complex improves the percutaneous absorption of DCF in human skin. It can also be used to form an inclusion complex with olanzapine (OLP) to increase its solubility for efficient drug delivery.

Other Notes

For R&D Use

Legal Information

Cavasol is a registered trademark of Wacker Chemie AG

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

368.6 °F

Flash Point(C)

187 °C

Certificate of Analysis

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Certificate of Origin

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