Merck
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809608

Sigma-Aldrich

Biotin-2′,2′,3′,3′-d4

≥98 atom % D, ≥95% (CP)

Synonym(s):
Vitamin H-d4, Vitamin B7-d4, Vitamin B8-d4
Empirical Formula (Hill Notation):
C10D4H12N2O3S
Molecular Weight:
248.34
PubChem Substance ID:
NACRES:
NA.12

Quality Level

isotopic purity

≥98 atom % D

assay

≥95% (CP)

form

powder

technique(s)

mass spectrometry (MS): suitable

color

white to off-white

mp

228 °C

mass shift

M+4

storage temp.

−20°C

SMILES string

OC(CC([2H])([2H])C([2H])([2H])C[C@@H]1SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1/i1D2,2D2

InChI key

YBJHBAHKTGYVGT-CCSQOTJNSA-N

Related Categories

General description

Biotin is a water-soluble vitamin B which is also known as vitamin B7. It is involved in the synthesis of fatty acids and gluconeogenesis. Biotin is found in plants and animals. Its deficiency causes retardation in growth, alopecia and neurological impairment in humans and animals.
Biotin-2′,2′,3′,3′-d4 is an isotope of vitamin B7 wherein C-2′, C-2′, C-3′, C-3′ protons are replaced by deuterium.

Application

Biotin-2′,2′,3′,3′-d4 can be used as a stable isotope internal standard for accurate data interpretation in specific biological samples.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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More Documents

Quotes and Ordering

A IJpelaar et al.
Clinical biochemistry, 83, 78-80 (2020-05-31)
Despite the increasing awareness about biotin interference with immunoassays, so far, only two studies have quantified the prevalence of elevated biotin in patient populations. In a US study, over 7% had biotin concentrations exceeding 10 ng/mL, whereas in an Australian study
Factitious Graves disease due to biotin immunoassay interference-a case and review of the literature
Elston MS, et al.
The Journal of clinical endocrinology and metabolism, 101(9), 3251-3255 (2016)
Agar plate method using Lactobacillus plantarum for biotin determination in serum and urine
FUKUI T, et al.
J. Nutr. Sci. Vitaminol., 40(5), 491-498 (1994)
Magnetic resonance imaging assays for dimethyl sulfoxide effect on cancer vasculature
Cyran CC, et al.
Investigative Radiology, 43(5), 298-298 (2008)

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