92361

Chlorotrimethylsilane

≥98.0% (GC)

• Synonym(s): TMCS, Trimethylchlorosilane, Trimethylsilyl chloride
• Linear Formula: (CH₃)₃SiCl
• CAS Number: 75-77-4
• Molecular Weight: 108.64
• Beilstein: 1209232
• EC Number: 200-900-5
• MDL number: MFCD00000502
• PubChem Substance ID: 57653472

Properties

• vapor density: 3.7 (vs air)
• Quality Level: 200
• vapor pressure: 100 mmHg ( 25 °C)
• Assay: ≥98.0% (GC)
• form: liquid
• autoignition temp.: 752 °F
• expl. lim.: 6.4 %
• refractive index: n20/D 1.387 (lit.)
• bp: 57 °C (lit.)
• mp: −40 °C (lit.)
• density: 0.856 g/mL at 25 °C (lit.)
• SMILES string: C[Si](C)(C)Cl
• InChI: 1S/C3H9ClSi/c1-5(2,3)4/h1-3H3
• InChI key: IJOOHPMOJXWVHK-UHFFFAOYSA-N

Description

General description

Chlorotrimethylsilane is a chloro-organosilane compound mainly used for silylation reactions.

Application

Chlorotrimethylsilane has been used to silanize glass surface to make them more hydrophobic. It can be used in combination with hexamethyldisilazane for the protection of alcohols by forming trimethylsilyl ethers via silylation reaction. Also used in Fisher Glycosylation

Safety Information

• Pictograms: GHS02,GHS05,GHS06
• Signal Word: Danger
• Hazard Statements: H225 - H301 + H331 - H312 - H314
• Precautionary Statements: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A
• Supplementary Hazards: EUH014
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): -18.4 °F - closed cup
• Flash Point(C): -28 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves