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M9768

Sigma-Aldrich

Cysteamine

~95%

Synonym(s):
2-Mercaptoethylamine, β-Mercaptoethylamine, MEA, Decarboxycysteine, 2-Aminoethanethiol, β-MEA, Thioethanolamine
Linear Formula:
NH2CH2CH2SH
CAS Number:
Molecular Weight:
77.15
Beilstein:
635649
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

~95%

storage temp.

2-8°C

SMILES string

NCCS

InChI

1S/C2H7NS/c3-1-2-4/h4H,1-3H2

InChI key

UFULAYFCSOUIOV-UHFFFAOYSA-N

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Application

Cysteamine is an amino thiol drug mainly used in the treatment of cystinosis. It is an antioxidant with chemo-sensitizing and radioprotective properties.

Packaging

5, 25, 50 g in glass bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M9768.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer.
Fujisawa T, et al.
PLoS ONE, 7(4), e34437-e34437 (2012)
Dandan Fang et al.
Mikrochimica acta, 186(9), 608-608 (2019-08-09)
An ultrasensitive competitive-type electrochemiluminescence immunoassay for the mycotoxin zearalenone is described. The method is based on the use of (a) a mimotope peptide that was selected from a phage displayed peptide library and used to substitute ZEN for designing the...
L Vécsei et al.
Progress in neuro-psychopharmacology & biological psychiatry, 14(6), 835-862 (1990-01-01)
1. Cysteamine is formed by degradation of coenzyme A (CoA) and causes somatostatin (SS), prolactin and noradrenaline depletion in the brain and peripheral tissues. 2. Cysteamine influences several behavioral processes, like active and passive avoidance behavior, open-field activity, kindled seizures...
Francesca Malvano et al.
Sensors (Basel, Switzerland), 18(7) (2018-07-07)
In this work, the development of an impedimetric label-free immunosensor for the detection of Escherichia coli O157:H7 is reported. Different immobilization techniques of monoclonal anti-E. coli were tested, in order to reach the very low limit of detections. The comparison...
C Gibrat et al.
Progress in neuro-psychopharmacology & biological psychiatry, 35(2), 380-389 (2010-11-30)
Neurodegenerative disorders are a subset of disabling pathologies characterized, in part, by a progressive and specific loss of certain brain cell populations. Current therapeutic approaches for the treatment of these disorders are mainly designed towards symptom management and do not...

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