W222305

Sigma-Aldrich

Tributyrin

97%, FG

Synonym(s):
Glycerol tributyrate, Glyceryl tributyrate, Tributyrin, 1,2,3-Tributyrylglycerol
Linear Formula:
(CH3CH2CH2COOCH2)2CHOCOCH2CH2CH3
CAS Number:
Molecular Weight:
302.36
FEMA Number:
2223
Beilstein/REAXYS Number:
1714746
EC Number:
Council of Europe no.:
747
MDL number:
PubChem Substance ID:
Flavis number:
9.211
NACRES:
NA.21

Quality Level

biological source

synthetic

grade

FG
Halal

reg. compliance

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 184.1903

assay

97%

refractive index

n20/D 1.435 (lit.)

bp

129-131 °C/0.03 mmHg (lit.)
287-288 °C (lit.)

density

1.032 g/mL at 20 °C (lit.)

Documentation

see Safety & Documentation for available documents

Featured Industry

Flavors and Fragrances

Organoleptic

creamy; fatty; waxy; cheesy

food allergen

no known allergens

SMILES string

CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC

InChI

1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3

InChI key

UYXTWWCETRIEDR-UHFFFAOYSA-N

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General description

Tributyrin is a short-chain triacylglycerol that mainly occurs in butter. It shows potent anti-cancer property.

Packaging

5, 10 kg in poly drum
1 kg in poly bottle

Biochem/physiol Actions

Taste at 30 ppm

Other Notes

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storage_class_code

10 - Combustible liquids

WGK Germany

WGK 1

Flash Point F

345.2 °F - closed cup

Flash Point C

174 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy.
Chen ZX & Breitman TR
Cancer Research, 54(13), 3494-3499 (1994)
Do-Won Jeong et al.
Food microbiology, 62, 92-98 (2016-11-28)
We assessed the safety of 49 Tetragenococcus halophilus strains isolated from doenjang in Korea. Minimum inhibitory concentration assays showed that all strains can be considered as susceptible to ampicillin, erythromycin, penicillin G, tetracycline, and vancomycin, but resistant to ciprofloxacin based...
Tania Diaz-Vidal et al.
Biotechnology progress, 35(4), e2807-e2807 (2019-03-19)
Despite the proven therapeutic role of capsaicin in human health, its usage is still hampered by its high pungency. In this sense, nonpungent capsaicin analogues as olvanil are a feasible alternative to the unpleasant sensations produced by capsaicin while maintaining...
Krzysztof Poszytek et al.
International journal of environmental research and public health, 15(7) (2018-07-18)
Sewage sludge is an abundant source of microorganisms that are metabolically active against numerous contaminants, and thus possibly useful in environmental biotechnologies. However, amongst the sewage sludge isolates, pathogenic bacteria can potentially be found, and such isolates should therefore be...
Anna Berthold-Pluta et al.
Foods (Basel, Switzerland), 8(7) (2019-07-25)
The prevalence of Bacillus cereus in a total of 585 samples of food products (herbs and spices, breakfast cereals, pasta, rice, infant formulas, pasteurized milk, fresh acid and acid/rennet cheeses, mold cheeses and ripening rennet cheeses) marketed in Poland was...

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