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T-111

Supelco

Tetrahydrocannabivarinic acid (THCVA) solution

1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

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Empirical Formula (Hill Notation):
C20H26O4
CAS Number:
Molecular Weight:
330.42
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

cannabis testing
cannabis testing

format

single component solution

shipped in

dry ice

storage temp.

−70°C

InChI

1S/C20H26O4/c1-5-6-12-10-15-17(18(21)16(12)19(22)23)13-9-11(2)7-8-14(13)20(3,4)24-15/h9-10,13-14,21H,5-8H2,1-4H3,(H,22,23)

InChI key

IQSYWEWTWDEVNO-UHFFFAOYSA-N

General description

This certified Snap-N-Spike® solution is suitable for THCVA testing methods by GC/MS, LC/MS, or HPLC for applications in clinical toxicology, testing of Cannabis potency or impurity profiling, pharmaceutical research, forensic analysis, and urine drug testing. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.

Tetrahydrocannabivarinic acid is the acidic precursor of the phytocannabinoid tetrahydrocannabivarin (THCV).

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Determination of 18 cannabinoids and their metabolites in 55 forensic serum samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • Screening and measuring 16 cannabinoids in cannabis plant materials, plant extracts, edible cannabis oils, and cannabis-based cosmetic products by 1H qNMR method and a novel 2D-COSY qNMR method
  • Development and validation of liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantifying 17 cannabinoids in cannabis and hemp samples
  • High-performance liquid chromatography-diode array detector (HPLC-DAD) method-based determination of 16 cannabinoids in hemp concentrates
  • Base-line separation and quantification of 18 cannabinoids by liquid chromatography-diode array detector (LC-DAD) method

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup


Certificates of Analysis (COA)

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Nimi Vashi et al.
The Journal of biological chemistry, 292(13), 5144-5165 (2017-02-09)
The role of Golgi apparatus during phagocytic uptake by macrophages has been ruled out in the past. Notably, all such reports were limited to Fcγ receptor-mediated phagocytosis. Here, we unravel a highly devolved mechanism for recruitment of Golgi-derived secretory vesicles
Shachar Jerushalmi et al.
Scientific reports, 11(1), 13973-13973 (2021-07-09)
Medical cannabis (MC) production is a rapidly expanding industry. Over the past ten years, many additional phytocannabinoids have been discovered and used for different purposes. MC was reported beneficial for the treatment of a variety of clinical conditions such as
Adela Constantinescu-Bercu et al.
eLife, 9 (2020-04-22)
Platelet-neutrophil interactions are important for innate immunity, but also contribute to the pathogenesis of deep vein thrombosis, myocardial infarction and stroke. Here we report that, under flow, von Willebrand factor/glycoprotein Ibα-dependent platelet 'priming' induces integrin αIIbβ3 activation that, in turn

Articles

We offer a portfolio of cannabinoid CRMs such as THC and THCA, available as single component solutions or mixes, certified in accordance with ISO 17034 and ISO/IEC 17025 for accurate cannabinoid profiling and potency testing.

A complete workflow for the HPLC separation of 17 cannabinoids in different cannabis products using Ascentis® Express C18 Column in a shorter run time with retention time stability. Learn more here.

An overview of gradient HPLC-based analysis of cannabinoids, optimized for key method parameters such as column temperature, mobile phase pH, and methanol as low-cost organic modifier. Learn more here.

An accurate and precise HPLC-PDA measurement of 32 cannabinoids and 2 cannflavins in hemp samples using a single extraction in less than 32 minutes.

Protocols

HPLC separation of 17 important cannabinoids including CBD, delta 9 THC and THCA. Read the application note

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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