1.00058

Acetic acid

96%, EMPROVE^® ESSENTIAL

• Synonym(s): Acetic acid, Ethanoic acid, Glacial acetic acid
• Linear Formula: CH₃CO₂H
• CAS Number: 64-19-7
• Molecular Weight: 60.05
• Beilstein: 506007
• MDL number: MFCD00036152

Properties

• vapor density: 2.07 (vs air)
• Quality Level: 500
• vapor pressure: 15.2 hPa ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• form: liquid
• autoignition temp.: 463 °C; 800 °F
• expl. lim.: 16 %, 92 °F; 4 %, 59 °F; 4-19.9 % (v/v)
• concentration: 96%
• refractive index: n20/D 1.371 (lit.)
• pH: 2.5 (20 °C, 10 g/L in H₂O)
• bp: 117-118 °C (lit.); 117.9 °C/1013 hPa
• mp: 16.2 °C (lit.); 16.6 °C
• transition temp: flash point 39 °C
• density: 1.05 g/cm³ at 20 °C; 1.049 g/mL at 25 °C (lit.)
• application(s): liquid formulation; pharmaceutical; semi-solid formulation
• storage temp.: 15-25°C
• SMILES string: CC(O)=O
• InChI: 1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
• InChI key: QTBSBXVTEAMEQO-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Acetic acid can be used as acidifying agent and buffer component in a variety of pharmaceutical formulations and production processes, including e.g. plasma fractionation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS05
• Signal Word: Danger
• Hazard Statements: H226 - H314
• Precautionary Statements: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 102.2 °F
• Flash Point(C): 39 °C