1.00574

1-Methyl-2-pyrrolidone

for Peptide Synthesis

• Synonym(s): 1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
• Empirical Formula (Hill Notation): C₅H₉NO
• CAS Number: 872-50-4
• Molecular Weight: 99.13
• MDL number: MFCD00003193
• EC Index Number: 212-828-1

Properties

• vapor pressure: 0.32 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥99.7% (GC)
• form: liquid
• autoignition temp.: 245 °C
• potency: 3598 mg/kg LD₅₀, oral (Rat); 8000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.3-9.5 % (v/v)
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• bp: 202 °C/1013 hPa
• mp: -24 °C
• transition temp: flash point 91 °C
• density: 1.03 g/cm³ at 20 °C
• application(s): peptide synthesis
• storage temp.: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• InChI key: SECXISVLQFMRJM-UHFFFAOYSA-N

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H315 - H319 - H335 - H360FD
• Precautionary Statements: P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point(F): 195.8 °F - Pensky-Martens closed cup
• Flash Point(C): 91 °C - Pensky-Martens closed cup