All Photos(2)

1.00577

Supelco

Water

for headspace gas chromatography SupraSolv®

Linear Formula:
H2O
CAS Number:
Molecular Weight:
18.02
Beilstein:
2050024
MDL number:

Quality Level

vapor pressure

23 hPa ( 20 °C)

product line

SupraSolv®

form

liquid

technique(s)

GC-HS: suitable

impurities

≤1 μg/g Every residual solvent of class 1 acc. to ICH
≤10 μg/g Every residual solvent of class 2 acc. to ICH
≤50 μg/g Every residual solvent of class 3 acc. to ICH

evapn. residue

≤5 mg/L

refractive index

n20/D 1.34 (lit.)

pH

7 (20 °C)

bp

100 °C (lit.)

mp

0 °C (lit.)

density

1.000 g/mL at 3.98 °C (lit.)

storage temp.

2-30°C

SMILES string

O

InChI

1S/H2O/h1H2

InChI key

XLYOFNOQVPJJNP-UHFFFAOYSA-N

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General description

SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all residual solvents defined by the ICH.

Analysis Note

residue on evaporation: ≤ 5 mg/l
GC/HS
Every residual solvent of class 1 acc. to ICH: ≤ 1 µg/g
Every residual solvent of class 2 acc. to ICH: ≤ 10 µg/g
Every residual solvent of class 3 acc. to ICH: ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1, 2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, N,N-dimethylacetamide, N,N-dimethy lformamide and dimethyl sulfoxide are not detected.

Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificate of Analysis

Certificate of Origin

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