Merck
All Photos(1)

516557

Sigma-Aldrich

Anti-PGC-1, C-Terminal (777-797) Rabbit pAb

liquid, Calbiochem®

Synonym(s):
Anti-Ligand Effect Modulator 6, Anti-PPARγ Coactivator 1

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−70°C

Gene Information

General description

Recognize the ~92-105 kDa (apparent MW) PGC-1 protein.
Immunoaffinity purified rabbit polyclonal antibody. Recognize the ~92-105 kDa (apparent MW) PGC-1 protein.
This Anti-PGC-1, C-Terminal (777-797) Rabbit pAb is validated for use in ELISA, Immunoblotting, Immunohistochemistry for the detection of PGC-1, C-Terminal (777-797).

Immunogen

Human
a synthetic peptide [(C)SKYDSLDFDSLLKEAQRSLRR] corresponding to amino acids 777-797 of the human PPARγ Coactivator 1 protein

Packaging

100 μL in Plastic ampoule

Application

ELISA (1:50,000)

Immunoblotting (1:1000)

Immunohistochemistry (1:300)

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Puigserver, P., et al. 1998. Cell 92, 829.
Variables associated with assay conditions will dictate the optimal working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Quality

Enter Lot Number to search for Certificate of Quality (COQ).

Kazuhiko Higashida et al.
PLoS biology, 11(7), e1001603-e1001603 (2013-07-23)
It has been reported that feeding mice resveratrol activates AMPK and SIRT1 in skeletal muscle leading to deacetylation and activation of PGC-1α, increased mitochondrial biogenesis, and improved running endurance. This study was done to further evaluate the effects of resveratrol
null
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Effect of exercise on mouse liver and brain bioenergetic infrastructures.
E, et al.
Experimental Physiology, 98, 207-219 (2018)
Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle.
Timmers, et al.
PLoS ONE, 6, e14503-e14503 (2018)

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