8.05894

4-Methylmorpholine

for synthesis

• Synonym(s): 4-Methylmorpholine, NMM, N-Methylmorpholine
• Empirical Formula (Hill Notation): C₅H₁₁NO
• CAS Number: 109-02-4
• Molecular Weight: 101.15
• MDL number: MFCD00006175
• EC Index Number: 203-640-0

Properties

• vapor pressure: 23.5 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥98% (GC)
• form: liquid
• autoignition temp.: 165 °C (DIN 51794)
• potency: 1960 mg/kg LD₅₀, oral (Rat); 1240 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 2.1 % (v/v)
• pH: 10.6 (20 °C, 50 g/L in H₂O)
• bp: 112-114 °C/1013 hPa
• mp: -66 °C
• transition temp: flash point 12.5 °C (DIN 51755 Part 1)
• density: 0.92 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C5H11NO/c1-6-2-4-7-5-3-6/h2-5H2,1H3
• InChI key: SJRJJKPEHAURKC-UHFFFAOYSA-N

Description

Application

4-Methylmorpholine can be used as:

• A precursor to prepare N-methylmorpholine N-oxide and 1-butyl-1-methylmorpholinium bromide ([BMmo][Br]), a monocation ionic liquid.[1][2]
• A reactant to synthesize quaternary ammonium complexes applicable as complexing agents in redox flow batteries.[3]
• A basic catalyst in the synthesis of thiobenzamides via Willgerodt-Kindler′s reaction.[4]
• An activating agent to synthesize hyaluronic acid-based biopolymer for cosmetic, pharmaceutical, and nutraceutical applications.[5]

Packaging

1, 2.5 l in Glass bottle

250 ml in Glass bottle

Analysis Note

Assay (GC, area%): ≥ 98 %
Density (d 20 °C/ 4 °C): 0.917 - 0.918
Identity (IR): passes test

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225 - H302 - H314
• Precautionary Statements: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 53.6 °F - DIN 51755 Part 1
• Flash Point(C): 12 °C - DIN 51755 Part 1