Merck
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8.22184

Sigma-Aldrich

TWEEN® 20

for synthesis

Synonym(s):
Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate
CAS Number:
MDL number:
EC Index Number:
500-018-3

Quality Level

vapor pressure

<1.4 hPa ( 20 °C)

form

liquid

potency

38900 mg/kg LD50, oral (Rat)

mol wt

~1228

refractive index

n20/D 1.468 (lit.)

pH

6-8 (20 °C, 50 g/L in H2O)

transition temp

flash point 275 °C

density

1.095 g/mL at 25 °C (lit.)

storage temp.

2-30°C

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

Tween®-20 is a polysorbate-based non-ionic surfactant. It is made up of three chemical units:
  • aliphatic ester chains that hinder biomolecules from nonspecific interactions
  • aliphatic chain that can be non-covalently adsorbed on a hydrophobic surface
  • hydrophilic terminal hydroxyl groups, which can be chemically modified for potential applications.

Application

Tween®-20 can be used as a structure-directing agent in the preparation of mesoporous oxide films because of its ability to promote textural properties of the films such as controllable crystallinity, film morphology, tailor-designed pore structure, high BET surface area, and controlled film thickness. It is also used in the synthesis of AuNPs/TWEEN/GO composites, where Tween®-20 acts as a reducing and immobilizing agent for AuNPs (Au nanoparticles) as well as a stabilizing agent for GO (graphene oxide).
Tween®-20 can also be used as an emulsifying, solubilizing, and wetting agent in a variety of liquid formulations.
Non-ionic detergent

Analysis Note

Density (d 20 °C/ 4 °C): 1.095 - 1.105
Hydroxyl value: 96 - 108
Saponification value: 40 - 50
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

527.0 °F - Pensky-Martens closed cup

Flash Point(C)

275 °C - Pensky-Martens closed cup

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