15522

D-(+)-Galactose

meets analytical specification of Ph. Eur., BP

• Synonym(s): Galactose
• Empirical Formula (Hill Notation): C₆H₁₂O₆
• CAS Number: 59-23-4
• Molecular Weight: 180.16
• Beilstein: 1724619
• EC Number: 200-416-4
• MDL number: MFCD00151230
• PubChem Substance ID: 57647466
• NACRES: NA.21

Properties

• Quality Level: 200
• quality: meets analytical specification of Ph. Eur., BP
• technique(s): IR spectroscopy: suitable
• impurities: acid. or alk. react. impurities, in accordance; microbiological impurity, in accordance; residual solvents, in accordance; ≤1.0% water (Karl Fischer)
• mp: 168-170 °C (lit.)
• solubility: H₂O: soluble 180 g/L at 20 °C
• suitability: in accordance for appearance of solution; in accordance for identity (IR)
• application(s): pharmaceutical (small molecule)
• SMILES string: OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
• InChI: 1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1
• InChI key: GZCGUPFRVQAUEE-KCDKBNATSA-N

Description

Application

D-(+)-Galactose was used for examining the specificity of staining with SBA-FITC during labeling of cells for fluorescence-activated cell sorting (FACS). It was used for selecting the transformed strains of S. cerevisiae.

Biochem/physiol Actions

Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.

Galactose is a monosaccharide sugar and is the natural antigen present on the blood cells. It induces memory loss, neurodegeneration as well as oxidative damage in mice due to systemic exposure.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves