Merck
  • 15604
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15604

Sigma-Aldrich

Urea

puriss., meets analytical specification of Ph. Eur., BP, USP, 99.0-100.5%, 99.0-101.0% (calc. on dry substance)

Synonym(s):
Carbamide, Carbonyldiamide
Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
Beilstein:
635724
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

puriss.

Quality Level

Assay

99.0-100.5%
99.0-101.0% (calc. on dry substance)

form

solid

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

alkalic reac. substances, complies
≤0.001% heavy metals (as Pb)
≤0.04% insoluble in ethanol
≤0.05% ammonium (NH4)
≤0.1% biuret(carbamylurea)

ign. residue

≤0.1% (as SO4)

loss

≤1.0% loss on drying, 105 °C, 1 h

mp

132-135 °C (lit.)
132-135 °C

solubility

H2O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤10 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Fe: ≤0.5 mg/kg

suitability

in accordance for appearance of solution
in accordance for identity

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

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This Item
U51281.04166U1250
Urea puriss., meets analytical specification of Ph. Eur., BP, USP, 99.0-100.5%, 99.0-101.0% (calc. on dry substance)

Sigma-Aldrich

15604

Urea

Urea ACS reagent, 99.0-100.5%

Sigma-Aldrich

U5128

Urea

Urea granulated, EMPROVE® EXPERT, Ph. Eur., BP, JP, USP, ACS

SAFC

1.04166

Urea

Urea ReagentPlus®, ≥99.5%, pellets

Sigma-Aldrich

U1250

Urea

grade

puriss.

grade

-

grade

-

grade

-

assay

99.0-100.5%, 99.0-101.0% (calc. on dry substance)

assay

99.0-100.5%

assay

-

assay

≥99.5%

form

solid

form

solid

form

granular

form

pellets

impurities

alkalic reac. substances, complies, ≤0.001% heavy metals (as Pb), ≤0.04% insoluble in ethanol, ≤0.05% ammonium (NH4), ≤0.1% biuret(carbamylurea)

impurities

≤0.01% Insoluble matter

impurities

-

impurities

-

mp

132-135 °C (lit.)

mp

132-135 °C (lit.)

mp

132-135 °C (lit.)

mp

132-135 °C (lit.)

solubility

H2O: soluble 480 g/L at 20 °C

solubility

H2O: soluble 480 g/L at 20 °C

solubility

-

solubility

H2O: 8 M

General description

Urea is a colorless, odorless solid. It has prism-like crystals. It forms insoluble nitrate salts with nitric acid and oxalate salts with oxalic acid. On reaction with alkanes or substituted alkanes, it affords crystal-lattice inclusion compounds.
Urea can be prepared from ammonia and carbon-dioxide, via Haber-Bosch process. It can also be used to prepare urea-formaldehyde resins, via condensation reaction.

Application

Urea has been used in the following studies:
  • Synthesis of SnO2 nanoparticles.
  • Synthesis of urethanes, ureides and semicarbazides.
  • Denaturation of protein isolated from Saccharomyces cerevisiae Y15696 strain
  • Protein electrophoretic studies.
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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