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33034

Sigma-Aldrich

L-Ascorbic acid

puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

Synonym(s):
Antiscorbutic factor, Vitamin C, L-Threoascorbic acid
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

biological source

synthetic

grade

ACS reagent
puriss. p.a.

Agency/Method

Ph. Eur.
USP/NF
reag. ISO

assay

99.7-100.5% (oxidimetric)

form

solid

optical activity

[α]20/D +20.5 to +21.5°, c = 10% in H2O

application(s)

IR spectroscopy: suitable
cell analysis: suitable

impurities

related substances, in accordance (HPLC)
≤0.001% heavy metals (by ICP-OES)

ign. residue

≤0.05% (as SO4)

loss

≤0.1% loss on drying, 105 °C

pH

2.1-2.6 (20 °C, 5%)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤20 mg/kg

cation traces

As: ≤1 mg/kg
Cu: ≤5 mg/kg
Fe: ≤2 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

suitability

complies for appearance of solution
passes test for identity (IR)

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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General description

L-Ascorbic acid or vitamin C is a water-soluble vitamin found in various foodstuffs. Benefits of vitamin C may include protection against immune system deficiencies, cardiovascular disease, hyperpigmentation, skin protection, anti-aging, iron absorption, and red blood cell production. It is also useful in the biosynthesis of collagen, L-carnitine, and neurotransmitters.

Application

L-Ascorbic acid has been used as an analytical interfering substance in glycated albumin (GA) enzymatic assay.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 1

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Testa R, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 1(2), 162-171 (2016)
T R Tickner et al.
Clinica chimica acta; international journal of clinical chemistry, 85(2), 125-129 (1978-04-17)
A new colorimetric method for the assay of biliverdin in biological fluids is described. The method, based upon the reaction of biliverdin with barbituric acid, offers improved sensitivity and selectivity when compared to direct spectrophotometric measurements. Using this method biliverdinaemia...
Total phenols, ascorbic acid, β-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities.
Barros L, et al.
Food Chemistry, 103(2), 413-419 (2007)
A family of mammalian NaI[plus]I-dependent L-ascorbic acid transporters.
Tsukaguchi H, et al.
Nature, 673(1), 70-75 (1999)
Jiali Zhang et al.
Chemical communications (Cambridge, England), 46(7), 1112-1114 (2010-02-04)
We demonstrated that the individual graphene oxide sheets can be readily reduced under a mild condition using L-ascorbic acid (L-AA). This simple approach should find practical applications in large scale production of water soluble graphene.

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