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372978

Chloroform

anhydrous, contains amylenes as stabilizer, ≥99%

Chloroform

Synonym(s):

Methylidyne trichloride, Trichloromethane

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About This Item

Empirical Formula (Hill Notation):
CHCl3
CAS Number:
67-66-3
Molecular Weight:
119.38
UNSPSC Code:
12191502
NACRES:
NA.21
PubChem Substance ID:
57649716
EC Number:
200-663-8
Beilstein/REAXYS Number:
1731042
MDL number:
MFCD00000826
Assay:
≥99%
Grade:
anhydrous
Bp:
60.5-61.5 °C (lit.)
Vapor pressure:
160 mmHg ( 20 °C)
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grade

anhydrous

Quality Level

200

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

assay

≥99%

form

liquid

contains

amylenes as stabilizer

packaging

Sure/Seal™ of 1, 6x1, 2 L, Pure-Pac® 2 of 20 L (USA only)

impurities

<0.001% water, 0.005% water (100mL)

evapn. residue

<0.0003%

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This Item
47247634854
Chloroform anhydrous, contains amylenes as stabilizer, &#8805;99%

Sigma-Aldrich

372978

Chloroform

Chloroform contains amylenes as stabilizer, ACS reagent, &#8805;99.8%

Sigma-Aldrich

472476

Chloroform

Chloroform suitable for HPLC, &#8805;99.8%, amylene stabilized

Sigma-Aldrich

34854

Chloroform

grade

anhydrous

grade

ACS reagent

grade

HPLC grade

assay

≥99%

assay

≥99.8%

assay

≥99.8%

Quality Level

200

Quality Level

200

Quality Level

100

form

liquid

form

liquid

form

liquid

mp

−63 °C (lit.)

mp

−63 °C (lit.)

mp

−63 °C (lit.)

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

General description

Chloroform is an organic solvent that can beproduced by the chlorination of methane or lower-chlorinated methanes.

Application

Chloroform can be used as a solvent:
  • To synthesize diaryl ketones.
  • In the palladium-catalyzed cross-coupling reaction of aryl­boronic acids with acid chlorides under the phosphine-free condition to synthesize aryl ketones.
It can also be used as a phosgene precursor in Friedel-Crafts-type aminocarbonylation.(3)

Packaging

View returnable container options.

Legal Information

Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany
Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

ppe

Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT5344
SHBT1756
SHBT1480
SHBT0515
SHBS9585

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Global Trade Item Number

SKUGTIN
372978-1L04061831834390
372978-12X100ML04061831834383
372978-2L04061831834406
372978-6X1L04061831834413
372978-100ML04061831834376
372978-200L-KL04061838152183
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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