Merck
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402907

Sigma-Aldrich

Propionic acid

ACS reagent, ≥99.5%

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Synonym(s):
Acid C3, Propanoic acid, Propanyl acid
Linear Formula:
CH3CH2COOH
CAS Number:
Molecular Weight:
74.08
Beilstein:
506071
EC Number:
MDL number:
eCl@ss:
39021305
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

vapor density

2.55 (vs air)

vapor pressure

2.4 mmHg ( 20 °C)

Assay

≥99.5%

form

liquid

autoignition temp.

955 °F

expl. lim.

12.1 %

analyte chemical class(es)

amino acids

impurities

≤0.002% Carbonyl compounds
≤0.10% Readily oxidizable substances (as HCOOH)
≤0.15% water

evapn. residue

≤0.01%

color

APHA: ≤20

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

solubility

H2O: soluble

density

0.993 g/mL at 25 °C (lit.)

cation traces

heavy metals (as Pb): ≤0.001%

SMILES string

CCC(O)=O

InChI

1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

InChI key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

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1 of 4

This Item
81910W292419W292400
Propionic acid ACS reagent, ≥99.5%

Sigma-Aldrich

402907

Propionic acid

Propionic acid puriss. p.a., ≥99.5% (GC)

Sigma-Aldrich

81910

Propionic acid

Propionic acid natural, 99%, FG

Sigma-Aldrich

W292419

Propionic acid

Propionic acid ≥99.5%, FCC, FG

Sigma-Aldrich

W292400

Propionic acid

form

liquid

form

liquid

form

-

form

-

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

bp

141 °C (lit.)

bp

141 °C (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

mp

−24-−23 °C (lit.)

mp

−24-−23 °C (lit.)

mp

−24-−23 °C (lit.)

solubility

H2O: soluble

solubility

organic solvents: soluble(lit.), water: soluble(lit.)

solubility

H2O: soluble

solubility

H2O: soluble

General description

Propionic acid (PA) also known as propanoic acid is a short chain fatty acid mainly used as food preservative. It is one of the main metabolic end product formed during the fermentation of undigested food in the colon by the microbiota. Its manufacture by glycerol/glucose co-fermentation using Propionibacterium acidipropionici has been reported. Crystal structure study reveals that PA crystals are monoclinic with space group P21/c.
Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst. PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions. Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.

Application

Propionic acid may be used to alter limestone in order to increase its ability of CO2 uptake.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

129.2 °F - closed cup

Flash Point(C)

54 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Derrick F MacFabe et al.
Behavioural brain research, 217(1), 47-54 (2010-10-13)
Recent evidence suggests that a variety of environmental factors, including dietary and gastrointestinal agents, may contribute to autism spectrum disorders (ASD). Here we administered propionic acid (PPA), a short chain fatty acid that is used as a food preservative and
The crystal structure of propionic acid.
Strieter FJ, et al.
Acta Crystallographica, 15(12), 1233-1239 (1962)
Yin Liu et al.
Current microbiology, 62(1), 152-158 (2010-06-15)
Cosubstrates fermentation is such an effective strategy for increasing subject metabolic products that it could be available and studied in propionic acid production, using glycerol and glucose as carbon resources. The effects of glycerol, glucose, and their mixtures on the
Enhancement of CO2 capture capacity by modifying limestone with propionic acid.
Sun R, et al.
Powder Technology, 233, 8-14 (2013)
Nucleophilic ?-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis
Jin, Zhichao, et al.
Chemistry?A European Journal , 21 (26), 9360-9363 (2015)

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