74595

Supelco

(±)-Glycidol

analytical standard

Synonym(s):
2,3-Epoxy-1-propanol, (±)-Oxirane-2-methanol, Glycerolglycide
Empirical Formula (Hill Notation):
C3H6O2
CAS Number:
Molecular Weight:
74.08
Beilstein/REAXYS Number:
383562
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

vapor density

2.15 (vs air)

vapor pressure

0.9 mmHg ( 25 °C)

assay

≥95.0% (GC)

form

neat

autoignition temp.

780 °F

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.429-1.437
n20/D 1.433 (lit.)

bp

61-62 °C/15 mmHg (lit.)

density

1.117 g/mL at 25 °C (lit.)

Featured Industry

Cleaning Products
Cosmetics
Food and Beverages
Personal Care

format

neat

SMILES string

OCC1CO1

InChI

1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2

InChI key

CTKINSOISVBQLD-UHFFFAOYSA-N

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General description

Glycidol is an aliphatic epoxide which may be used as a stabilizer in the manufacture of vinyl polymers, as an additive for oil and synthetic hydraulic fluids, and also as a diluent in some epoxy resins.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

hazcat

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK Germany

WGK 3

Flash Point F

161.6 °F

Flash Point C

72 °C

Certificate of Analysis

Certificate of Origin

NTP Toxicology and Carcinogenesis Studies of Glycidol (CAS No. 556-52-5) In F344/N Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program and others
National Toxicology Program Technical Report Series, 374(3), 1-1 (1990)
Carcinogenicity of glycidol in F344 rats and B6C3F1 mice.
Irwin RD, et al.
Journal of Applied Toxicology, 16(3), 201-209 (1996)
Hirotoshi Akane et al.
Journal of applied toxicology : JAT, 34(12), 1389-1399 (2014-01-08)
We previously found that exposure to glycidol at 1000 ppm in drinking water caused axonopathy in maternal rats and aberrations in late-stage hippocampal neurogenesis, targeting the process of neurite extension in offspring. To identify the profile of developmental neurotoxicity of...
Glycidol.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 469-486 (2000-12-02)
Kunio Wada et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 769, 1-6 (2014-10-26)
The in vivo comet assay has been used for the evaluation of DNA damage and repair in various tissues of rodents. However, it can give false-positive results due to non-specific DNA damage associated with cell death. In this study, we...

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