Merck
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79109

Supelco

2-Ethoxyethanol

analytical standard

Synonym(s):
Ethylene glycol monoethyl ether, Ethyl glycol
Linear Formula:
C2H5OCH2CH2OH
CAS Number:
Molecular Weight:
90.12
Beilstein:
1098271
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

vapor density

3.1 (vs air)

vapor pressure

3.8 mmHg ( 20 °C)

assay

≥99.8% (GC)

autoignition temp.

460 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

14 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.407 (lit.)
n20/D 1.408

bp

135 °C (lit.)

mp

−90 °C (lit.)

density

0.93 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

CCOCCO

InChI

1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

InChI key

ZNQVEEAIQZEUHB-UHFFFAOYSA-N

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General description

2-Ethoxyethanol is an organic compound, widely used as a component or solvent for nitrocellulose and in a variety of dyes, inks, cleaning agents, resins, paints, varnishes, etc. It is also used for increasing the stability of emulsions.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
2-Ethoxyethanol may be used as an extraction solvent for the quantification and analysis of algal lipids from algae samples using normal-phase high performance liquid chromatography(HPLC) coupled in parallel to an evaporative light scattering detector (ELSD) and quadrupole mass spectrometer(QMS).

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F

Flash Point(C)

40 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Extraction of algal lipids and their analysis by HPLC and mass spectrometry
Jones J, et al.
Journal of the American Oil Chemists' Society, 89(8), 1371-1381 (2012)
Rui-Sheng Wang et al.
Industrial health, 45(4), 574-578 (2007-09-20)
Ethylene glycol monoethyl ether (EGEE) can cause damage to testes and sperm, and its metabolites are believed to play an important role in its toxicity. Aldehyde dehydrogenase 2 (ALDH2) is involved in the metabolism of this chemical. To investigate whether
Matthew J Traynor et al.
Toxicology and applied pharmacology, 218(2), 128-134 (2006-12-19)
Glycol ethers are solvents widely used alone and as mixtures in industrial and household products. Some glycol ethers have been shown to have a range of toxic effects in humans following absorption and metabolism to their aldehyde and acid metabolites.
David J Lockley et al.
Toxicology and applied pharmacology, 180(2), 74-82 (2002-04-24)
Percutaneous absorption and cutaneous metabolism of 2-ethoxyethanol were assessed in vivo and with an in vitro flow-through diffusion system. Topical application of undiluted (14)C-ethoxyethanol to occluded rat skin in vivo resulted in 25% of the dose being absorbed after 24
I A Adedara et al.
Andrologia, 45(2), 111-119 (2012-06-20)
Endocrine disrupting chemicals cause reproductive dysfunction by interacting with intricate regulation and cellular processes involve in spermatogenesis. This study investigated the probable mechanism of action of ethylene glycol monoethyl ether (EGEE) as an antiandrogenic compound as well as the effects

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