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puriss. p.a., ACS reagent, ≥99.5% (GC)

1,2-PDO, Propylene glycol
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


ACS reagent
puriss. p.a.

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)


≥99.5% (GC)


viscous liquid

autoignition temp.

779 °F

shelf life

3 yr

expl. lim.

12.5 %


≤0.003% free acid (as CH3COOH)
≤0.1% water

evapn. residue


ign. residue

<0.005% (as SO4)

refractive index

n20/D 1.432 (lit.)
n20/D 1.433


187 °C (lit.)


−60 °C (lit.)


1.036 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤1 mg/kg
sulfate (SO42-): ≤20 mg/kg

cation traces

Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤5 mg/kg

SMILES string




InChI key


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General description

1,2-Propanediol is a 1,2-alkanediol. It can be obtained from glycerol, via hydrogenolysis in the presence of Ru/C and Amberlyst ion-exchange resins.


1,2-Propanediol (propanediol) may be employed as a cryoprotective agent for the preservation (by cooling to sub-zero temperatures) of human embryos and oocytes (human and mouse).

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 82280.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit

Storage Class Code

10 - Combustible liquids



Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Alexander Eberle et al.
Journal of the American Chemical Society, 140(4), 1327-1336 (2018-01-10)
Supramolecular self-assembly at the solid-solid interface enables the deposition and monolayer formation of insoluble organic semiconductors under ambient conditions. The underlying process, termed as the organic solid-solid wetting deposition (OSWD), generates two-dimensional adsorbates directly from dispersed three-dimensional organic crystals. This
Verya Daeichin et al.
IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 64(3), 555-567 (2017-01-24)
Although high-frequency ultrasound imaging is gaining attention in various applications, hardly any ultrasound contrast agents (UCAs) dedicated to such frequencies (>15 MHz) are available for contrast-enhanced ultrasound (CEUS) imaging. Moreover, the composition of the limited commercially available UCAs for high-frequency
Jeffrey J Kim et al.
Tobacco induced diseases, 15, 14-14 (2017-02-28)
Despite the rising health and safety concerns of e-cigarettes, a universal e-cigarette testing method is still in its early developmental stage. The aim of this study was to develop an e-liquid Reference Material that can be used to improve accuracy
D A Gook et al.
Human reproduction (Oxford, England), 8(7), 1101-1109 (1993-07-01)
Human and mouse oocytes were cryopreserved by a slow freeze, rapid thaw method, using propanediol (PROH) as the cryoprotectant. A simulated cryopreservation was also included in the study to detect the level of damage attributable to the PROH alone. Comparison
Iban Seiliez et al.
Autophagy, 12(2), 343-356 (2016-02-24)
Monitoring autophagic flux in vivo or in organs remains limited and the ideal methods relative to the techniques possible with cell culture may not exist. Recently, a few papers have demonstrated the feasibility of measuring autophagic flux in vivo by

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