All Photos(3)

B3420

Sigma-Aldrich

Sodium benzoate

BioXtra, ≥99.5%

Synonym(s):
Benzoic acid sodium salt
Linear Formula:
C6H5COONa
CAS Number:
Molecular Weight:
144.10
Beilstein:
3572467
EC Number:
MDL number:
eCl@ss:
39024301
PubChem Substance ID:
NACRES:
NA.25

Quality Level

product line

BioXtra

assay

≥99.5%

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

>300 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.10%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

[Na+].[O-]C(=O)c1ccccc1

InChI

1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1

InChI key

WXMKPNITSTVMEF-UHFFFAOYSA-M

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General description

Sodium benzoate is a safe food preservative and has antimicrobial functionality. It has a molecular weight of 114.11 Da. Sodium benzoate is used in bakery products, juice and cheese. In the liver, it is conjugated to glycine and is eliminated as hippuric acid from the urine.

Application

Sodium benzoate has been used to test its effect on phencyclidine (PCP) induced locomotor activity in mice.

Packaging

250 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Sodium benzoate also has pharmaceutical applications and is component of syrup and transparent tablet. High levels of sodium benzoate may trigger histamine release and also induce cell damage. It is recommended for the treatment of urea cycle disorders. However, high levels of sodium benzoate may contribute to glycine deficiency and may impose neuromodulatory effects.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Benzoate and sorbate salts: a systematic review of the potential hazards of these invaluable preservatives and the expanding spectrum of clinical uses for sodium benzoate
Piper JD and Piper PW
Comprehensive Reviews in Food Science and Food Safety, 16(5), 868-880 (2017)
Modulating NMDA receptor function with D-amino acid oxidase inhibitors: understanding functional activity in PCP-treated mouse model
Sershen H, et al.
Neurochemical Research, 41(1-2), 398-408 (2016)
An Overview on the Effects of Sodium Benzoate as a Preservative in Food Products
Shahmohammadi M, et al.
Biotechnology and Health Sciences, 3(3), 7-11 (2016)
Matteo Gabba et al.
Biophysical journal, 118(2), 422-434 (2019-12-18)
We present a fluorescence-based approach for determination of the permeability of small molecules across the membranes of lipid vesicles and living cells. With properly designed experiments, the method allows us to assess the membrane physical properties both in vitro and in vivo....
Jia Li et al.
Environmental science and pollution research international, 18(9), 1567-1573 (2011-05-18)
This study investigated the effect of copper on chemical oxygen demand (COD) removal efficiency and on the properties (mainly settling and dewatering) and the composition of extracellular polymeric substances (EPS) when 20 mg/L Cu(II) was continuously dosed to a sequencing...

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