Merck
All Photos(3)

H3660

Sigma-Aldrich

Hydroquinone

meets USP testing specifications

Synonym(s):
1,4-Benzenediol, HQ, 1,4-Dihydroxybenzene
Linear Formula:
C6H4-1,4-(OH)2
CAS Number:
Molecular Weight:
110.11
Beilstein:
605970
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Agency

USP/NF
meets USP testing specifications

vapor density

3.81 (vs air)

vapor pressure

1 mmHg ( 132 °C)

assay

99.0-100.5% anhydrous basis

autoignition temp.

930 °F

bp

285 °C (lit.)

mp

172-175 °C (lit.)

suitability

suitable for pesticide residue analysis

application(s)

pharmaceutical (small molecule)

SMILES string

Oc1ccc(O)cc1

InChI

1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H

InChI key

QIGBRXMKCJKVMJ-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

329.0 °F - closed cup

Flash Point(C)

165 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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P Carbonnelle et al.
Toxicology and applied pharmacology, 132(2), 220-226 (1995-06-01)
Decreased interleukin-1 (IL-1) production by mononuclear phagocytes has been shown to contribute to benzene myelotoxicity in animals. The study presented here was designed to examine the relevance of this mechanism in humans. Fresh human blood monocytes were exposed to 0.001-10
Yaqi Hu et al.
Biosensors & bioelectronics, 47, 45-49 (2013-04-03)
A novel light "on-off" photoelectrochemical sensing for the sensitive determination of hydroquinone was developed based on the porphyrin-functionalized Au nanoparticles on graphene (porphyrin/AuNPs/graphene). Gold nanoparticles (AuNPs) were firstly modified onto graphene sheets using NaBH4 as reductant and the porphyrin/AuNPs/graphene nanocomposites
A P DeCaprio
Critical reviews in toxicology, 29(3), 283-330 (1999-06-24)
Hydroquinone (HQ) is a high-volume commodity chemical used as a reducing agent, antioxidant, polymerization inhibitor, and chemical intermediate. It is also used in over-the-counter (OTC) drugs as an ingredient in skin lighteners and is a natural ingredient in many plant-derived
Jacob Levitt
Journal of the American Academy of Dermatology, 57(5), 854-872 (2007-05-01)
Recently, the US Food and Drug Administration proposed a ban on over-the-counter hydroquinone mainly on the basis of high absorption, reports of exogenous ochronosis in humans, and murine hepatic adenomas, renal adenomas, and leukemia with large doses over extended time
Nuan P Cheah et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(3), 1072-1081 (2013-02-19)
Tobacco smoke consists of thousands of harmful components. A major class of chemicals found in tobacco smoke is formed by aldehydes, in particular formaldehyde, acetaldehyde and acrolein. The present study investigates the gene expression changes in human lung alveolar epithelial

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