I0100000

All Photos(1)

I0100000

Imipramine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride, 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride

Empirical Formula (Hill Notation):

C₁₉H₂₄N₂ · HCl

CAS Number:

113-52-0

Molecular Weight:

316.87

MDL number:

MFCD00012669

PubChem Substance ID:

329815297

NACRES:

NA.24

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Hydrochlorothiazide

grade

pharmaceutical primary standard

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2CCc3ccccc13

InChI

1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

InChI key

XZZXIYZZBJDEEP-UHFFFAOYSA-N

Gene Information

human ... SLC6A2(6530) , SLC6A4(6532)

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Pharmacopeia & Metrological Institute Standards

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This Item	BP932	PHR1797	I7379
I0100000 Imipramine hydrochloride	BP932 Imipramine hydrochloride	Supelco PHR1797 Imipramine Hydrochloride	Sigma-Aldrich I7379 Imipramine hydrochloride
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade -
manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename -	manufacturer/tradename -
application(s) pharmaceutical (small molecule)	application(s) -	application(s) pharmaceutical (small molecule)	application(s) -
format neat	format neat	format neat	format -
Gene Information human ... SLC6A2(6530), SLC6A4(6532)	Gene Information human ... SLC6A2(6530), SLC6A4(6532)	Gene Information human ... SLC6A2(6530), SLC6A4(6532)	Gene Information human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), SLC6A2(6530), SLC6A4(6532)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters with K_is of 7.7 nM and 67 nM, respectively. Has little effect on the dopamine transporter (K_i = 25 μM).

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300

Precautionary Statements

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)