Merck
All Photos(5)

L5626

Sigma-Aldrich

L-Lysine monohydrochloride

reagent grade, ≥98% (HPLC)

Synonym(s):
(S)-2,6-Diaminohexanoic acid monohydrochloride
Linear Formula:
H2N(CH2)4CH(NH2)CO2H·HCl
CAS Number:
Molecular Weight:
182.65
Beilstein:
3563889
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

grade

reagent grade

assay

≥98% (HPLC)

form

powder

technique(s)

immunohistochemistry: suitable

color

white to off-white

mp

263 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

OC([C@@H](N)CCCCN)=O.[H]Cl

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

InChI key

BVHLGVCQOALMSV-JEDNCBNOSA-N

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Application

L-lysine monohydrochloride has been used:
  • as a component in pre-fixative solution for electron microscopy
  • as a component in blocking solution for immunohistochemistry(IHC)
  • in the preparation of Periodate-lysine-paraformaldehyde (PLP) fixative for IHC

Packaging

1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drum

Biochem/physiol Actions

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Arginine and lysine reduce the high viscosity of serum albumin solutions for pharmaceutical injection
Inoue N, et al.
Journal of Bioscience and Bioengineering, 117(5), 539-543 (2014)
Multispectral imaging of T and B cells in murine spleen and tumor
Feng Z, et al.
Journal of Immunology, 1502635-1502635 (2016)
Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans
Smriga M, et al.
Biomedical Research, 28(2), 85-90 (2007)
Isolates with low-level vancomycin resistance associated with persistent methicillin-resistant Staphylococcus aureus bacteremia
Howden BP, et al.
Antimicrobial Agents and Chemotherapy, 50(9), 3039-3047 (2006)
Medicinal uses of L-Lysine: Past and future
Singh M, et al.
International Journal of Research in Pharmaceutical Sciences, 2(4), 637-642 (2016)

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