Merck
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P2126

Sigma-Aldrich

L-Phenylalanine

reagent grade, ≥98%

Synonym(s):
(S)-2-Amino-3-phenylpropionic acid
Linear Formula:
C6H5CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
165.19
Beilstein:
1910408
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

grade

reagent grade

assay

≥98%

form

powder or crystals

color

white to off-white

mp

270-275 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

application(s)

detection

SMILES string

N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1

InChI key

COLNVLDHVKWLRT-QMMMGPOBSA-N

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Application

L-Phenylalanine has been used in Fluo-4 Ca2+-assay in a study to demonstrate that G-protein coupled receptor 139 reference surrogate agonists 1a and 7c and L-phenylalanine share a common binding site. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening.

Packaging

1 kg in poly bottle
100, 500 g in poly bottle

Biochem/physiol Actions

L-Phenylalanine is an essential aromatic amino acid. It has a role in metabolism as it forms a starting point for many pathways. This neutral amino acid is a precursor for tyrosine, epinephrine, dopamine and norepinephrine.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Anne Cathrine
Scientific Reports (2017)
Effect of Dried Blood Spot Quality on Newborn Screening Analyte Concentrations and Recommendations for Minimum Acceptance Criteria for Sample Analysis
Roanna S. George, Stuart J. Moat
Clinical Chemistry (2016)
AMINO ACIDS | Metabolism
Encyclopedia of Food and Color Additives, 197-206 (2003)
Protein and Amino Acid Metabolism
ESSENTIALS OF MEDICINAL CHEMISTRY null
Genetics in Medicine : Official Journal of the American College of Medical Genetics (2012)

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