P2126

L-Phenylalanine

reagent grade, ≥98%

• Synonym(s): (S)-2-Amino-3-phenylpropionic acid
• Linear Formula: C₆H₅CH₂CH(NH₂)CO₂H
• CAS Number: 63-91-2
• Molecular Weight: 165.19
• Beilstein: 1910408
• EC Number: 200-568-1
• MDL number: MFCD00064227
• eCl@ss: 32160406
• PubChem Substance ID: 24898274
• NACRES: NA.26

Properties

• grade: reagent grade
• Quality Level: 200
• Assay: ≥98%
• form: powder or crystals
• color: white to off-white
• mp: 270-275 °C (dec.) (lit.)
• solubility: 1 M NH4OH: 50 mg/mL, clear, colorless
• application(s): detection
• SMILES string: N[C@@H](Cc1ccccc1)C(O)=O
• InChI: 1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
• InChI key: COLNVLDHVKWLRT-QMMMGPOBSA-N
• Gene Information: human ... CA1(759) , CA14(23632) , CA2(760) , CA4(762) , CA5A(763) , CA7(766)

Description

Application

L-Phenylalanine has been used in Fluo-4 Ca²⁺-assay in a study to demonstrate that G-protein coupled receptor 139 reference surrogate agonists 1a and 7c and L-phenylalanine share a common binding site. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening.

Biochem/physiol Actions

L-Phenylalanine is an essential aromatic amino acid. It has a role in metabolism as it forms a starting point for many pathways. This neutral amino acid is a precursor for tyrosine, epinephrine, dopamine and norepinephrine.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves