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PHR1327

Supelco

Ammonium chloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Ammonium chloride, Salmiac
Linear Formula:
NH4Cl
CAS Number:
Molecular Weight:
53.49
Beilstein:
4371014
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

vapor density

1.9 (vs air)

vapor pressure

1 mmHg ( 160.4 °C)

form

neat

CofA

current certificate can be downloaded

application(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

340 °C (subl.) (lit.)

Featured Industry

Cleaning Products
Cosmetics
Food and Beverages
Personal Care
Pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to USP 1029953

SMILES string

N.Cl

InChI

1S/ClH.H3N/h1H;1H3

InChI key

NLXLAEXVIDQMFP-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ammonium chloride is formed as a by-product during soda manufacturing by Solvay process. It can be synthesized by reacting HCl with aqueous ammonia solutions. Crystals of ammonium chloride (NH4Cl) belong to the cubic crystal system.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA0830 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

Alexander J F Egan et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8197-8202 (2014-05-14)
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Chloé Lescale et al.
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The Journal of experimental medicine, 211(10), 1925-1935 (2014-09-03)
Allogeneic hematopoietic stem cell (HSC) transplantation (HSCT) is currently the leading strategy to manage acute myeloid leukemia (AML). However, treatment-related morbidity limits the patient generalizability of HSCT use, and the survival of leukemic stem cells (LSCs) within protective areas of...

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