R2751

Sigma-Aldrich

Ruthenium Red

Technical grade

Synonym(s):
Ammoniated ruthenium oxychloride
Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
Molecular Weight:
786.35
Colour Index Number:
77800
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

assay

34-39% ruthenium (Ru) basis (ICP)

form

powder

application(s)

hematology: suitable
histology: suitable

solubility

water: 10 mg/mL

εmax

200-750 at 533-534 nm

Featured Industry

Diagnostic Assay Manufacturing

storage temp.

room temp

SMILES string

N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]

InChI

1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6

InChI key

ZXYSDUPLHOJIOR-UHFFFAOYSA-H

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General description

Ruthenium Red is a hexavalent polysaccharide stain. It inhibits mitochondrial Ca2+ uniporter. It is a capsaicin antagonist and blocks vanilloid receptor-1 (VR-1)-coupled ion channels.

Application

Ruthenium Red has been used for microscopic characterization of cotton tip morphology. It has also been used as a TRPV2 channel blocker.
Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

Packaging

1, 5 g in glass bottle

pictograms

Exclamation mark

signalword

Warning

hcodes

hazcat

Acute Tox. 4 Oral

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

George Goodwin et al.
Neuroscience, 429, 10-22 (2019-12-25)
Radiating pain is a significant feature of chronic musculoskeletal pain conditions such as radiculopathies, repetitive motion disorders and whiplash associated disorders. It is reported to be caused by the development of mechanically-sensitive ectopic receptive fields along intact nociceptor axons at...
Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release
Jae Hoon Bae
Biochemical and Biophysical Research Communications, 303 (2003)
Ruthenium red as a capsaicin antagonist.
Amann R and Maggi CA
Life Sciences, 49(12) (1991)
Cotton fiber tips have diverse morphologies and show evidence of apical cell wall synthesis
Michael R. Stiff and Candace H. Haigler
Scientific Reports (2016)
Gregory M Pask et al.
PloS one, 6(12), e28774-e28774 (2011-12-17)
Insect odorant receptors (ORs) function as odorant-gated ion channels consisting of a conventional, odorant-binding OR and the Orco coreceptor. While Orco can function as a homomeric ion channel, the role(s) of the conventional OR in heteromeric OR complexes has largely...

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