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Sodium valproate

European Pharmacopoeia (EP) Reference Standard

2-propylpentanoic acid sodium, Sodium 2-propylpentanoate, Sodium valproate, Valproic acid sodium salt
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
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PubChem Substance ID:


pharmaceutical primary standard




pharmaceutical (small molecule)



storage temp.


SMILES string




InChI key


Gene Information

human ... ALDH5A1(7915)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder.


Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.


Other Notes

Sales restrictions may apply.


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Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class Code

11 - Combustible Solids



Certificate of Analysis

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Certificate of Origin

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More documents

Quotes and Ordering

Kristen A Wellmann et al.
Brain research bulletin, 108, 1-9 (2014-08-19)
Prenatal exposure to valproic acid (VPA) alters rodent social interactions in a dose-dependent way: exposure to a high dose of VPA (>500 mg/kg) mid-gestation decreases social interactions whereas a moderate dose of VPA (350 mg/kg) increases peer-directed social behavior. The
Pengfei Shi et al.
BMC cancer, 14, 370-370 (2014-06-03)
Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, is reported to exert anti-tumor effects by upregulating the expression of the natural killer group 2D (NKG2D) ligands on tumor cells; however, the mechanisms vary in different tumor types, and the effect
Péter Pelsőczi et al.
Frontiers in behavioral neuroscience, 13, 295-295 (2020-02-06)
Autism spectrum disorder (ASD) is characterized by impaired socio-communicational function, repetitive and restricted behaviors. Valproic acid (VPA) was reported to increase the prevalence of ASD in humans as a consequence of its use during pregnancy. VPA treatment also induces autistic-like
Peter Štefánik et al.
Pharmacology, biochemistry, and behavior, 131, 42-50 (2015-02-11)
Autism is a neurodevelopmental disorder characterised by the disruption of social interactions. Autistic animal models play a crucial role in neurophysiologic research on this disorder. One of these models is based on rats that have been prenatally treated with valproic
Osvaldo Garrido-Acosta et al.
Journal of pharmacological and toxicological methods, 70(1), 66-69 (2014-05-27)
We determined the median effective dose (ED50) values for the anticonvulsants phenobarbital and sodium valproate using a modification of Lorke's method. This modification allowed appropriate statistical analysis and the use of a smaller number of mice per compound tested. The

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