Merck
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S4641

Sigma-Aldrich

Sodium citrate tribasic dihydrate

ACS reagent, ≥99.0%

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Synonym(s):
Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate
Linear Formula:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS Number:
Molecular Weight:
294.10
Beilstein:
6104939
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

Agency

suitable for SM 4500 - NH3

Assay

≥99.0%

impurities

≤0.003% Ammonia (NH3)
≤0.005% Insoluble matter

pH

7.0-9.0 (25 °C, 5% in solution)

mp

>300 °C (lit.)

solubility

water: soluble 29.4 g/L at 20 °C (completely)

anion traces

chloride (Cl-): ≤0.003%
sulfate (SO42-): ≤0.005%

cation traces

Ca: ≤0.005%
Fe: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

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This Item
C72547140571406
assay

≥99.0%

assay

≥98%

assay

≥99.0% (NT)

assay

≥99.0% (NT)

impurities

≤0.003% Ammonia (NH3), ≤0.005% Insoluble matter

impurities

-

impurities

11-13% water (KFT)

impurities

-

pH

7.0-9.0 (25 °C, 5% in solution)

pH

7.5-9 (25 °C, 29.4 g/L)

pH

7.0-9.0 (25 °C, 50 mg/mL in H2O)

pH

7.0-9.0 (25 °C, 50 mg/mL in H2O)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

solubility

water: soluble 29.4 g/L at 20 °C (completely)

solubility

water: soluble 100 mg/mL

solubility

water: soluble 29.4 g/L at 20 °C

solubility

water: very soluble 24.9 g/L at 20 °C

Application

Sodium citrate tribasic dihydrate can be used as a catalyst to synthesize:     
  • Fused O- and N-heterocyclic derivatives via multicomponent Knoevenagel-cyclocondensation of isatin/aldehyde/ acenaphthylene-1,2-dione, malononitrile, and various C−H activated acids.     
  • Chromeno[3′,4′:5,6]pyrano[2,3-d]pyrimidines by the condensation reaction of 4-hydroxycoumarin, aromatic aldehydes, and barbituric acid/thiobarbituric acid.

It can also be used as:      
A reducing agent to synthesize metal nanoparticles via sol-gel method using corresponding metal salt precursors.    
A controlling agent in the synthesis of single-crystal of coordination polymer [Co(H2O)2Ni(CN)4 4H2O].

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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