Y0000883

Adrenaline with impurity F

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
(−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine, (−)-Epinephrine
Linear Formula:
(HO)2C6H3CH(OH)CH2NHCH3
CAS Number:
Molecular Weight:
183.20
Beilstein/REAXYS Number:
2368277
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

form

neat

manufacturer/tradename

EDQM

mp

215 °C (dec.) (lit.)

Featured Industry

Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChI key

UCTWMZQNUQWSLP-VIFPVBQESA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Adrenoceptor agonist.

Packaging

Unit quantity: 0.008 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones

signalword

Danger

hazcat

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

storage_class_code

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK Germany

WGK 3

Certificate of Analysis

Certificate of Origin

Lisa Hartling et al.
The Cochrane database of systematic reviews, (6)(6), CD003123-CD003123 (2011-06-17)
Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. We searched CENTRAL (2010, Issue 3) which contains the Acute Respiratory Infections Group's...
Aziz Sheikh et al.
The Cochrane database of systematic reviews, 8(8), CD008935-CD008935 (2012-08-17)
Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may cause death. Adrenaline (epinephrine) auto-injectors are recommended as the initial, potentially life-saving treatment of choice for anaphylaxis in the community, but they are not universally available and...
Shinji Nakahara et al.
BMJ (Clinical research ed.), 347, f6829-f6829 (2013-12-12)
To evaluate the effectiveness of pre-hospital adrenaline (epinephrine) administered by emergency medical services to patients with out of hospital cardiac arrest. Controlled propensity matched retrospective cohort study, in which pairs of patients with or without (control) adrenaline were created with...
Phillip L Lieberman
The American journal of medicine, 127(1 Suppl), S6-11 (2014-01-05)
The International Classification of Diseases (ICD)-9 included a code only for anaphylactic shock. The improved ICD-10 coding defines the different symptoms and types of anaphylaxis and includes coding for anaphylaxis without shock. This new coding is consistent with the efforts...
A Sheikh et al.
Allergy, 64(2), 204-212 (2009-01-31)
Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. Adrenaline is recommended as the initial treatment of choice for anaphylaxis. To assess the benefits and harms of adrenaline in the treatment of anaphylaxis. We...

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