Merck
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128082

Sigma-Aldrich

2-Ethoxyethanol

ReagentPlus®, 99%

Synonym(s):
Ethylene glycol monoethyl ether, Ethyl glycol
Linear Formula:
C2H5OCH2CH2OH
CAS Number:
Molecular Weight:
90.12
Beilstein:
1098271
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

vapor density

3.1 (vs air)

vapor pressure

3.8 mmHg ( 20 °C)

product line

ReagentPlus®

assay

99%

form

liquid

autoignition temp.

460 °F

expl. lim.

14 %

technique(s)

UV/Vis spectroscopy: suitable

impurities

<0.10% water

refractive index

n20/D 1.407 (lit.)

bp

135 °C (lit.)

mp

−90 °C (lit.)

solubility

water: miscible

density

0.93 g/mL at 25 °C (lit.)

SMILES string

CCOCCO

InChI

1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

InChI key

ZNQVEEAIQZEUHB-UHFFFAOYSA-N

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General description

2-Ethoxyethanol is a glycol ether. It has been reported as a precursor for ethoxyacetic acid (EAA). Various physical properties (density, refractive index, viscosity and speed of sound) of its binary mixtures with n-alkanes, 2,2,4-trimethylpentane and cyclohexane have been evaluated. High-pressure vapor-liquid equilibrium (VLE) data of its binary mixtures with CO2 have been reported. It can be used as a solvent in the spectrophotometric determination of iron(III) by using the ligand, N,N-bis(2-hydroxy-5-bromo-benzyl)1,2 diaminopropane (HBDAP).

Application

2-Ethoxyethanol (Ethylene glycol monoethyl ether) has been used in zebrafish embryotoxicity test (ZET). It can act like a co-surfactant in the separation of highly hydrophobic analytes via microemulsion electrokinetic chromatography and solvent-modified micellar electrokinetic chromatography.

Packaging

1, 4 L in glass bottle
500 mL in glass bottle
25 L in steel drum

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F

Flash Point(C)

40 °C

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

"Selective preconcentration, separation and speciation of ferric iron in different samples using N, N'-bis (2-hydroxy-5-bromo-benzyl) 1, 2 diaminopropane"
Kara D and Alkan
Talanta, 55(2), 415-423 (2001)
"Comparison of microemulsion electrokinetic chromatography and solvent-modified micellar electrokinetic chromatography"
Hansen HS, et al.
Journal of Separation Science, 24(8), 643-650 (2001)
Measurements and correlation of high-pressure VLE of binary CO2-alcohol systems (methanol, ethanol, 2-methoxyethanol and 2-ethoxyethanol).
Joung SN, et al.
Fluid Phase Equilibria, 185(1), 219-230 (2001)
Density, Viscosity, Refractive Index, and Speed of Sound in Binary Mixtures of 2-Ethoxyethanol with n-Alkanes (C6 to C12), 2, 2, 4-Trimethylpentane, and Cyclohexane in the Temperature Interval 298.15-313.15 K.
Aminabhavi TM and Gopalakrishna B.
Journal of Chemical and Engineering Data, 40(3), 632-641 (1995)
Rui-Sheng Wang et al.
Industrial health, 45(4), 574-578 (2007-09-20)
Ethylene glycol monoethyl ether (EGEE) can cause damage to testes and sperm, and its metabolites are believed to play an important role in its toxicity. Aldehyde dehydrogenase 2 (ALDH2) is involved in the metabolism of this chemical. To investigate whether

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