190764

Sigma-Aldrich

2-Propanol

ACS reagent, ≥99.5%

Synonym(s):
IPA, isopropanol, Isopropanol, sec-Propyl alcohol, Isopropyl alcohol
Linear Formula:
(CH3)2CHOH
CAS Number:
Molecular Weight:
60.10
Beilstein/REAXYS Number:
635639
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

ACS reagent

vapor density

2.1 (vs air)

vapor pressure

33 mmHg ( 20 °C)
44 mmHg ( 25 °C)

assay

≥99.5%

form

liquid

autoignition temp.

750 °F

expl. lim.

2.0-12.7 %, 93 °C

application(s)

RNA extraction: suitable

impurities

≤0.0001 meq/g Titr. acid or base
≤0.002% carbonyl compounds (as propionaldehyde or acetone)
≤0.2% water

evapn. residue

≤0.001%

color

APHA: ≤10

refractive index

n20/D 1.377 (lit.)

pH

7.0 (20 °C)

bp

82 °C (lit.)

mp

−89.5 °C (lit.)

solubility

H2O: passes test

density

0.785 g/mL at 25 °C (lit.)

SMILES string

CC(C)O

InChI

1S/C3H8O/c1-3(2)4/h3-4H,1-2H3

InChI key

KFZMGEQAYNKOFK-UHFFFAOYSA-N

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General description

2-Propanol is a secondary alcohol. It has been tested as a substitute fuel for use in various fuel cells. CuO powder dissolved in 2-propanol has been used for the laser ablation assisted synthesis of Cu colloids. Suspension of 2-propanol with Zn(NO3)2 has been employed for the fabrication of titanium dioxide-coated stainless steel (P25-TiO2/SS) photoanode coated with a uniformly thick layer of P25-TiO2. This photoanode was used for the electrochemical photocatalytic (ECPC) degradation process.

Application

2-propanol may be used in the synthesis of methyl isobutyl ketone with satisfactory yield in the presence of bifunctional Cu-base catalysts. It can undergo oxidation in the presence of titanium oxide-supported manganese oxide to form acetone. IPA may also be used as a solvent to synthesize cyclic ureas by reacting CO2 with diamines in the presence of pure cerium oxide.
2-Propanol (Isopropanol, Isopropyl alcohol) has been employed for RNA extraction in various studies.

Packaging

4×4 L in poly bottle
500, 6×500 mL in glass bottle
1, 6×1, 2.5, 4, 4×4 L in glass bottle
18, 200 L in steel drum

pictograms

FlameExclamation mark

signalword

Danger

hazcat

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 1

Flash Point F

53.6 °F - closed cup

Flash Point C

12.0 °C - closed cup

Certificate of Analysis

Certificate of Origin

Felix Moltzahn et al.
Journal of visualized experiments : JoVE, (54)(54), doi:10-doi:10 (2011-08-19)
The broad involvement of miRNAs in critical processes underlying development, tissue homoeostasis and disease has led to a surging interest among the research and pharmaceutical communities. To study miRNAs, it is essential that the quantification of microRNA levels is accurate...
Michelle T Paulsen et al.
Methods (San Diego, Calif.), 67(1), 45-54 (2013-08-27)
Gene expression studies commonly examine total cellular RNA, which only provides information about its steady-state pool of RNA. It remains unclear whether differences in the steady-state reflects variable rates of transcription or RNA degradation. To specifically monitor RNA synthesis and...
A study of anatase-supported Mn oxide as catalysts for 2-propanol oxidation.
Gallardo-Amores JM, et al.
Applied Catalysis. B, Environmental, 22(4), 249-259 (1999)
Highly efficient synthesis of cyclic ureas from CO2 and diamines by a pure CeO2 catalyst using a 2-propanol solvent.
Tamura M, et al.
Green Chemistry, 15(6), 1567-1577 (2013)
Formation and characteristics of Cu colloids from CuO powder by laser irradiation in 2-propanol.
Yeh MS, et al.
The Journal of Physical Chemistry B, 103(33), 6851-6857 (1999)

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