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34858

Sigma-Aldrich

Ethyl acetate

suitable for HPLC, ≥99.7%

Synonym(s):
EtOAc
Linear Formula:
CH3COOC2H5
CAS Number:
Molecular Weight:
88.11
Beilstein:
506104
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

3 (20 °C, vs air)

Quality Level

vapor pressure

73 mmHg ( 20 °C)

Assay

≥99.7%

form

liquid

autoignition temp.

801 °F

expl. lim.

2.2-11.5 %, 38 °F

technique(s)

GC/MS: suitable
HPLC: suitable

impurities

≤0.0005% non-volatile matter
≤0.005% free acid (as CH3COOH)
≤0.03% water (Karl Fischer)

refractive index

n20/D 1.3720 (lit.)

bp

76.5-77.5 °C (lit.)

mp

−84 °C (lit.)

density

0.902 g/mL at 25 °C (lit.)

UV absorption

λ: 255 nm Amax: ≤0.70
λ: 260 nm Amax: ≤0.30
λ: 270 nm Amax: ≤0.10
λ: 300 nm Amax: ≤0.01
λ: 400 nm Amax: ≤0.01

application(s)

food and beverages

format

neat

storage temp.

room temp

SMILES string

CCOC(C)=O

InChI

1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3

InChI key

XEKOWRVHYACXOJ-UHFFFAOYSA-N

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439169494518650528
Ethyl acetate suitable for HPLC, ≥99.7%

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vapor pressure

73 mmHg ( 20 °C)

vapor pressure

73 mmHg ( 20 °C)

vapor pressure

73 mmHg ( 20 °C)

vapor pressure

73 mmHg ( 20 °C)

assay

≥99.7%

assay

≥99.8%

assay

≥99.8%

assay

99.9%

form

liquid

form

liquid

form

liquid

form

liquid

autoignition temp.

801 °F

autoignition temp.

801 °F

autoignition temp.

801 °F

autoignition temp.

801 °F

expl. lim.

2.2-11.5 %, 38 °F

expl. lim.

2.2-11.5 %, 38 °F

expl. lim.

2.2-11.5 %, 38 °F

expl. lim.

2.2-11.5 %, 38 °F

General description

Ethyl acetate is an effective alternate solvent of diethyl ether.

Application

Ethyl acetate has been used as solvent for the isolation of Rose hip (Rosa canina L., Rosaceae) powder, via sonication. It has been used as solvent for the abstraction of volatile thiols from wine for their quantitative estimation by gas chromatography/mass spectrometry (GC-MS).

Other Notes

Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.
Important notice
  • The article number 34858-4X2.5L will be discontinued. Please order the single bottle 34858-2.5L which is physically identical with the same exact specifications.
  • The article number 34858-6X1L will be discontinued. Please order the single bottle 34858-1L which is physically identical with the same exact specifications.

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Pure-Pac is a registered trademark of Sigma-Aldrich Co. LLC

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

24.8 °F

Flash Point(C)

-4 °C


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Maria Nikolantonaki et al.
Analytica chimica acta, 660(1-2), 102-109 (2010-01-28)
As volatile thiols are nucleophiles, they are capable of additional reactions with electrophiles. In enology, this concerns reactions between volatile or non-volatile thiols and oxidized phenolic compounds. Initial studies concerning the reactivity of volatile thiols with polyphenols showed that (+)-catechin
Lasse Saaby et al.
Phytotherapy research : PTR, 25(2), 195-201 (2010-07-16)
A previously published systematic review and a metaanalysis have concluded that the consumption of standardized rose hip powder (Rosa canina L.) can reduce pain in osteoarthritis patients. Synovial inflammation has been suggested to play an important role in the pathogenesis
K H Young et al.
Journal of clinical microbiology, 10(6), 852-853 (1979-12-01)
Ethyl acetate appears to be a satisfactory subsitute solvent for diethyl ether in the Formalin-ether sedimentation technique. In comparative studies, concentration of organisms with ethyl acetate was equal to or greater than that with diethyl ether. No distortion or alteration
Tsukasa Horiyama et al.
PloS one, 9(9), e108642-e108642 (2014-09-27)
Escherichia coli produces the iron-chelating compound enterobactin to enable growth under iron-limiting conditions. After biosynthesis, enterobactin is released from the cell. However, the enterobactin export system is not fully understood. Previous studies have suggested that the outer membrane channel TolC
Flavio G Rocha et al.
Biomaterials, 29(19), 2884-2890 (2008-04-09)
Our group has previously created a functional neointestine that is capable of restoring absorptive function. However, the endogenous level of vascular endothelial growth factor (VEGF) is markedly reduced in the construct compared to native bowel. Therefore, we wanted to locally

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