259853

Sigma-Aldrich

Castor oil

CAS Number:
EC Number:
MDL number:
NACRES:
NA.21

Quality Level

biological source

synthetic (organic)

form

liquid

optical activity

[α]20/D +5°, c = 5 in ethanol

refractive index

n20/D 1.478 (lit.)

bp

313 °C (lit.)

density

0.961 g/mL at 25 °C

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Application

Castor oil is a triglyceride obtained from Ricinus communis. It has been used to study its impact on rat lens condition. Castor oil has also been used as a test reagent for studying the dose-response relationship and mechanism of action of Saccharomyces boulardii by utilizing the rat model of castor oil-induced diarrhea.

Packaging

1 L in glass bottle
250 mL in glass bottle

storage_class_code

10 - Combustible liquids

WGK Germany

awg

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Yumiao Zhang et al.
Nature communications, 7, 11649-11649 (2016-05-20)
Injectable hydrophobic drugs are typically dissolved in surfactants and non-aqueous solvents which can induce negative side-effects. Alternatives like 'top-down' fine milling of excipient-free injectable drug suspensions are not yet clinically viable and 'bottom-up' self-assembled delivery systems usually substitute one solubilizing...
Philippe Girard et al.
Digestive diseases and sciences, 48(4), 770-774 (2003-05-14)
For biotherapeutic agents, there is a lack of information on dose-response relationships and mechanism of action. The present study was designed to address these issues for Saccharomyces boulardii using the rat model of castor oil-induced diarrhea. A single dose of...
Thomas Holm et al.
PloS one, 8(11), e79620-e79620 (2013-11-22)
Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The...
Atul Pandey et al.
Hormones and behavior, 117, 104602-104602 (2019-10-28)
Juvenile hormone (JH) is a key regulator of insect development and reproduction. Given that JH commonly affects adult insect fertility, it has been hypothesized to also regulate behaviors such as dominance and aggression that are associated with reproduction. We tested...
Yun Zhou et al.
Neurochemistry international, 123, 22-33 (2018-07-28)
Glutamate-ammonia ligase (glutamine synthetase; Glul) is enriched in astrocytes and serves as the primary enzyme for ammonia detoxification and glutamate inactivation in the brain. Loss of astroglial Glul is reported in hippocampi of epileptic patients, but the mechanism by which...

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