Merck
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30461

Sigma-Aldrich

DEAE-Dextran hydrochloride

BioReagent, for molecular biology

Synonym(s):
Diethylaminoethyl-dextran hydrochloride
CAS Number:
MDL number:
NACRES:
NA.25

grade

for molecular biology

product line

BioReagent

form

solid

impurities

DNases, none detected
RNases, none detected
phosphatases, none detected
proteases, none detected

solubility

H2O: 0.1 g/mL, clear

storage temp.

room temp

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Application

DEAE-Dextran, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

S Tabor et al.
Current protocols in immunology, Chapter 10, Unit 10-Unit 10 (2008-04-25)
Extensive knowledge of the enzymology involved in biosynthesis and degradation of nucleic acids has permitted the development of simple methods for labeling RNA and DNA with radioisotopes or biotin. These labeled probes are used primarily for hybridization to nucleic acid
Transfection using DEAE-dextran.
Gulick T.
Current Protocols in Cell Biology, doi: 10-doi: 10 (2003)
DEAE-dextran transfection of lymphocyte cell lines.
Smale ST.
Cold Spring Harbor Protocols, doi: 10-doi: 10 (2010)
J Zarate et al.
Journal of microencapsulation, 28(7), 614-620 (2011-07-12)
Bovine serum albumin (BSA) loaded calcium alginate microparticles (MPs) produced in this study by a w/o emulsification and external gelation method exhibited spherical and fairly smooth and porous morphology with 1.052 ± 0.057 µm modal particle size. The high permeability of the calcium
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were

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