31170

Sigma-Aldrich

2-Deoxy-D-ribose

≥99.0% (TLC)

Synonym(s):
2-Deoxy-D-arabinose, 2-Deoxy-D-erythropentose, Thyminose
Empirical Formula (Hill Notation):
C5H10O4
CAS Number:
Molecular Weight:
134.13
Beilstein/REAXYS Number:
1721978
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥99.0% (TLC)

optical activity

[α]20/D −56±2°, 24 hr, c = 1% in H2O

ign. residue

≤0.5% (as SO4)

loss

≤1% loss on drying, 20 °C (HV)

mp

89-90 °C (lit.)

storage temp.

room temp

SMILES string

OC[C@@H](O)[C@@H](O)CC=O

InChI

1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m0/s1

InChI key

ASJSAQIRZKANQN-CRCLSJGQSA-N

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Related Categories

Application

2-Deoxy-D-ribose is used to study processes of oxidative stress and glycation in vivo and in vitro. 2-Deoxy-D-ribose, an endothelial-cell chemoattractant and angiogenesis-inducing factor, is used to study processes of tumor angiogenesis and progression mediated at the level of thymidine phosphorylase activity.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 31170.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Marina Rossi et al.
Physical review letters, 110(10), 107801-107801 (2013-03-26)
Concentrated solutions of ultrashort duplex-forming DNA oligomers may develop various forms of liquid crystal ordering among which is the chiral nematic phase, characterized by a macroscopic helical precession of molecular orientation. The specifics of how chirality propagates from the molecular...
Xican Li
Food chemistry, 141(3), 2083-2088 (2013-07-23)
The deoxyribose degradation assay is widely used to evaluate the hydroxyl (OH) radical-scavenging ability of food or medicines. We compared the hydroxyl radical-scavenging activity of 25 antioxidant samples prepared in ethanol solution with samples prepared after removing the ethanol (residue)....
Jean Cadet et al.
Free radical research, 46(4), 367-381 (2012-01-24)
A broad scientific community is involved in investigations aimed at delineating the mechanisms of formation and cellular processing of oxidatively generated damage to nucleic acids. Perhaps as a consequence of this breadth of research expertise, there are nomenclature problems for...
Waseem Hassan et al.
Chemico-biological interactions, 199(2), 96-105 (2012-06-12)
The study was designed to explore the biochemical influence of non bonding nitrogen interactions (N⋯Se/S) on organochalcogens potency. Approximately five and six times higher thiol peroxidase (TPx) like activity was observed for compound (C)-2 than C-1 and C-3, respectively. C-2...
Buthina Al-Oudat et al.
Bioorganic & medicinal chemistry letters, 23(3), 854-859 (2012-12-26)
Well-defined substrates for the study of oxidative processes are important for the elucidation of the role of DNA damage in the etiology of diseases such as cancer. We have synthesized 3'-modified oligodeoxyribonucleotides (ODNs) using 5'→3' 'reverse' DNA synthesis for the...

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