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Merck

50227

Sigma-Aldrich

D-Luciferin potassium salt

≥98.0% (HPLC)

Synonym(s):

(S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid potassium salt, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid potassium salt, Firefly luciferin potassium salt

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About This Item

Empirical Formula (Hill Notation):
C11H7KN2O3S2
CAS Number:
115144-35-9
Molecular Weight:
318.41
Beilstein:
5416262
MDL number:
MFCD00044928
UNSPSC Code:
12352106
PubChem Substance ID:
329757580
NACRES:
NA.32

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Quality Level

100

Assay

≥98.0% (HPLC)

form

powder or crystals

solubility

water: soluble

storage temp.

−20°C

SMILES string

[K+].Oc1ccc2nc(sc2c1)C3=N[C@H](CS3)C([O-])=O

InChI

1S/C11H8N2O3S2.K/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1

InChI key

UMBKGTQQGYPQBE-OGFXRTJISA-M

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1 of 4

This Item
L6882L6152L9504
D-Luciferin potassium salt ≥98.0% (HPLC)

Sigma-Aldrich

50227

D-Luciferin potassium salt

D-Luciferin sodium salt lyophilized powder, synthetic

Sigma-Aldrich

L6882

D-Luciferin sodium salt

D-Luciferin synthetic, BioXtra, ≥99% (HPLC)

Sigma-Aldrich

L6152

D-Luciferin

D-Luciferin synthetic

Sigma-Aldrich

L9504

D-Luciferin

assay

≥98.0% (HPLC)

assay

≥98% (HPLC)

assay

≥99% (HPLC)

assay

≥98% (HPLC)

solubility

water: soluble

solubility

H2O: soluble

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

300

form

powder or crystals

form

lyophilized powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Application

D-Luciferin may be used as a substrate in luciferase-based (EC 1.13.12.7) bioluminescence imaging and cell-based high-throughput screening applications. ATP can be measured with a reagent made up of D-luciferin and luciferase from firefly.D-Luciferin may be used and studied as a partial agonist for G protein-coupled receptor-35 (GPR35).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL4309
BCCL1495
BCCH6168
BCBV5337
BCBV2217

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Bruce R Branchini et al.
Scientific reports, 8(1), 5990-5990 (2018-04-18)
Effective methods for monitoring eukaryotic gene expression and regulation based on bioluminescence - the emission of light by living organisms - are well established. Typically, the expression of a gene of interest is reported on with high sensitivity and over
Mayu Yasunaga et al.
BMC biotechnology, 17(1), 54-54 (2017-06-24)
Three-dimensional (3D) spheroids are frequently used in toxicological study because their morphology and function closely resemble those of tissue. As these properties are maintained over a long term, repeated treatment of the spheroids with a test object is possible. Generally
Yun-Jung Chiang et al.
Oncogene, 38(9), 1432-1447 (2018-09-30)
High-frequency relapse remains a clinical hurdle for complete remission of T-cell acute lymphoblastic leukemia (T-ALL) patients, with heterogeneous dysregulated signaling profiles-including of Raf-MEK-ERK and Akt-mTORC1-S6K signaling pathways-recently being implicated in disease outcomes. Here we report that GM-CSF/IL-3/IL-5 receptor common β-chain-associated
A B Madhankumar et al.
PloS one, 13(1), e0181529-e0181529 (2018-01-06)
Peripheral nerve sheath tumors are benign tumors that have the potential to transform into malignant peripheral nerve sheath tumors (MPNSTs). Interleukin-13 receptor alpha 2 (IL13Rα2) is a cancer associated receptor expressed in glioblastoma and other invasive cancers. We analyzed IL13Rα2
Cristina Henriques et al.
Parasites & vectors, 5, 214-214 (2012-09-28)
Usually the analysis of the various developmental stages of Trypanosoma cruzi in the experimentally infected vertebrate and invertebrate hosts is based on the morphological observations of tissue fragments from animals and insects. The development of techniques that allow the imaging
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