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EX-CELL® Antifoam

gamma irradiated


Quality Level


sterile; γ-irradiated




NMR: suitable
cell culture | mammalian: suitable
protein quantification: suitable


suitable for manufacturing use

shipped in



EX-CELL® ANTIFOAM is a USP Grade non-ionic emulsion (simethicone) designed for use in the pharmaceutical and veterinary biological industries to aid in the control of foaming typically associated with the use of culture medium in bioreactors.
Through formulation optimization, utilization of a quantitative assay and an understanding of the nonspecific binding of simethicone, SAFC is able to report the actual simethicone concentration of the gamma irradiated finished material. As a result of this development, SAFC offers an optimized formulation ensuring a consistent product.
This product is of non-animal origin formulated from a 30% Simethicone Emulsion from DOW CORNING Q7-2587

Legal Information

EX-CELL is a registered trademark of Sigma-Aldrich Co. LLC

Storage Class Code

12 - Non Combustible Liquids

WGK Germany


Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

Bioreactor productivity and media cost comparison for different intensified cell culture processes.
Xu S et al.
Biotechnology Progress, doi: 10-doi: 10 (2016)
A practical approach in bioreactor scale-up and process transfer using a combination of constant P/V and vvm as the criterion.
Xu S et al.
Biotechnology Progress, doi: 10-doi: 10 (2017)
High-density mammalian cell cultures in stirred-tank bioreactor without external pH control.
Xu S and Chen H
Journal of Biotechnology, 231, 149-149 (2016)
David N Powers et al.
Biotechnology progress, 35(6), e2894-e2894 (2019-08-20)
Real-time monitoring of cell cultures in bioreactors can enable expedited responses necessary to correct potential batch failure perturbations which may normally go undiscovered until the completion of the batch and result in failure. Currently, analytical technologies are dedicated to real-time...

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