All Photos(5)

A2218

Sigma-Aldrich

L-Ascorbic acid

meets USP testing specifications

Synonym(s):
Antiscorbutic factor, Vitamin C, L-Threoascorbic acid
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

biological source

synthetic

Agency/Method

USP/NF
meets USP testing specifications

assay

99.0-100.5%

form

solid

application(s)

cell culture | mammalian: suitable

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

Featured Industry

Pharmaceutical (small molecule)

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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General description

L-ascorbic acid (AA) is a naturally occurring C vitamer. It is soluble in water. It is present in fruits and vegetables.

Application

L-ascorbic acid has been used as a supplement in DMEM/F12/ osteoblast induction medium. It has also been used as a component in liquid Ham′s isolation media.

Packaging

25, 100, 500 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

L-ascorbic acid (AA) can block and treat scurvy. It possesses antioxidant properties. In the fermentation of wine, AA acid serve as a food additive and antioxidant.
Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Compositional analysis of foods
Liquid Chromatography (2013)
An improved protocol for the isolation and cultivation of embryonic mouse myocytes
Rodgers LS, et al.
Cytotechnology, 59(2), 93-102 (2009)
1, 3, 2-Dioxathiolane oxides: epoxide equivalents and versatile synthons
Lohray BB and Bhushan V
Advances in Heterocyclic Chemistry, 68, 90-181 (1997)
Analysis of vitamins by liquid chromatography
Liquid Chromatography, 571-615 (2017)
Biological characteristics of muscle-derived satellite cells isolated from rats at different postnatal days
Yu R, et al.
Cytotechnology, 67(3), 397-408 (2015)

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