Merck
All Photos(3)

A7219

Sigma-Aldrich

L-Aspartic acid

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Synonym(s):
(S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid
Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
133.10
Beilstein:
1723530
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.75

biological source

non-animal source

Quality Level

Agency

meets EP testing specifications
meets USP testing specifications

assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

1 M HCl: 100 mg/mL

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

Gene Information

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General description

Aspartic acid(ASP)/aspartate, a non-essential amino acid, is naturally produced by mammals. ASP is one of the 20 building-block amino acids of proteins and has a one letter code, D. L-Aspartic acid can be manufactured industrially by an enzymatic process using the aspartase enzyme.

Application

L-Aspartic acid has been used:
  • as an aspartame (ASP) metabolite to determine acetylcholinesterase (AChE) activity in the hippocampal homogenate of suckling rats
  • as printed chemotaxis ligands to screen chemotaxis receptors with high-throughput technologies and verify the interactions with surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR)
  • as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) for supplementation assays of various cultured cell lines

Packaging

100 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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