A9165

N-Acetyl-L-cysteine

suitable for cell culture, BioReagent

• Synonym(s): LNAC, NAC
• Linear Formula: HSCH₂CH(NHCOCH₃)CO₂H
• CAS Number: 616-91-1
• Molecular Weight: 163.19
• Beilstein: 1724426
• EC Number: 210-498-3
• MDL number: MFCD00004880
• PubChem Substance ID: 24891402
• NACRES: NA.26

Properties

• product line: BioReagent
• Quality Level: 200
• Assay: ≥99% (TLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• color: white to off-white
• mp: 106-108 °C (lit.)
• solubility: H₂O: 100 mg/mL (with heating)
• storage temp.: 2-8°C
• SMILES string: CC(=O)N[C@@H](CS)C(O)=O
• InChI: 1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
• InChI key: PWKSKIMOESPYIA-BYPYZUCNSA-N

Description

Application

N-Acetyl-L-cysteine has been used as a component of intestinal basal medium for the culture of mouse intestinal stem cells and also as a component of expansion medium.

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves