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Benzalkonium chloride


Alkylbenzyldimethylammonium chloride, Alkyldimethylbenzylammonium chloride
Linear Formula:
C6H5CH2N(CH3)2RCl (R=C8H17 to C18H37)
CAS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level



product line



95.0-105.0% (calculated on dry substance)




≤0.001% Phosphate
≤0.1% Insoluble matter
≤10% water

ign. residue


anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string




InChI key


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General description

Benzalkonium chloride is a cationic detergent that is a member of quaternary ammonium compounds (QACs).


Benzalkonium chloride has been used in a study to assess its action on epithelia conjunctival cells in vitro. It has also been used in a study to investigate its effects on living rabbit cornea by in vivo Tandem scanning confocal microscopy.

Signal Word


Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible, corrosive hazardous materials



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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Dana Cervinkova et al.
Microbial drug resistance (Larchmont, N.Y.), 19(3), 160-167 (2012-12-22)
Conditions facilitating resistance to quaternary ammonium compounds (QACs) were investigated in Staphylococcus aureus SK982 exposed to benzalkonium chloride (BAC; a member of QACs) under various circumstances. S. aureus SK982 carrying the qacA gene encoding for resistance to QACs was grown
Céline Portal et al.
PloS one, 12(3), e0174764-e0174764 (2017-03-30)
Modification of mucous cell density and gel-forming mucin production are established hallmarks of mucosal diseases. Our aim was to develop and validate a mouse model to study live goblet cell density in pathological situations and under pharmacological treatments. We created
Eric G Romanowski et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 35(5), 311-314 (2019-04-11)
Purpose: Adenoviral conjunctivitis is the most common cause of conjunctivitis worldwide with no approved antiviral treatment. Benzalkonium chloride (BAK)
Ian Morrissey et al.
PloS one, 9(1), e86669-e86669 (2014-01-28)
To date there are no clear criteria to determine whether a microbe is susceptible to biocides or not. As a starting point for distinguishing between wild-type and resistant organisms, we set out to determine the minimal inhibitory concentration (MIC) and
A Kalkanci et al.
Journal de mycologie medicale, 25(4), 280-286 (2015-10-01)
The aim of this study was to determine the susceptibility of 77 mould strains: Aspergillus fumigatus (20), Aspergillus flavus (8), Aspergillus niger (4), Aspergillus ochraceus (2), Penicillium citrinum (15), Penicillium crysogenum (14), Penicillium aurantiogriseum (1), Penicillium roquefortii (4), Penicillium paneum

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