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Merck

C3821

Citrate-dextrose solution (ACD)

sterile-filtered

Synonym(s):

Acid citrate-dextrose, Anticoagulant citrate-dextrose

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About This Item

CAS Number:
UNSPSC Code:
12161700
NACRES:
NA.25
MDL number:
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Product Name

Citrate-dextrose solution (ACD), sterile-filtered

sterility

sterile-filtered

form

liquid

pH

4.5-5.5

storage temp.

2-8°C

Quality Level

Application

Citrate-dextrose solution (ACD) has been used for dilution of blood for haematological studies. It has also been used as an anticoagulant during blood collection by cardiac puncture from mice and human bone marrow isolation.
For research use only. Not for use in diagnostic procedures.

Biochem/physiol Actions

Useful for anticoagulation of whole blood; erythrocyte survival

General description

Citrate-dextrose solution (ACD) is an anticoagulant and preservative used routinely for blood storage. The ideal red blood cells shelf life is 21 days when stored in ACD solution. Red blood cells in ACD solution utilize glucose and their viability is impairs when reinfused.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Isolation, expansion and characterisation of mesenchymal stem cells from human bone marrow, adipose tissue, umbilical cord blood and matrix: a comparative study
Secunda R, et al.
Cytotechnology, 67(5), 793-807 (2015)
Mingming Yang et al.
Experimental and therapeutic medicine, 20(2), 1253-1260 (2020-08-09)
The p53 gene is well known as a key tumor suppressor gene; it is vital for hematopoietic stem cell differentiation and growth. In the present study, the change of platelets (PLTs) in p53 knockout mice (p53-/- mice) was investigated. The
The storage of hard-packed red blood cells in citrate-phosphate-dextrose (CPD) and CPD-adenine (CPDA-1)
Beutler E and West C
Blood, 54(1), 280-284 (1979)
Hideki Miyachi et al.
International journal of cardiology, 266, 61-66 (2018-06-12)
Acute thrombosis is a crucial cause of bioresorbable vascular graft (BVG) failure. Bone marrow-derived mononuclear cell (BM-MNC)-seeded BVGs demonstrated high graft patency, however, the effect of seeded BM-MNCs against thrombosis remains to be elucidated. Thus, we evaluated an antithrombotic effect
Comparison of equine platelet function and survival in whole blood collected in acid-citrate-dextrose solution or citrate-phosphate-dextrose-adenine solution
Bozorgmanesh R, et al.
Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology, 46(2), 262-268 (2017)

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