C8052
Cholera Toxin
from Vibrio cholerae, ≥90% (SDS-PAGE), lyophilized powder, A-B type toxin
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product name
Cholera Toxin from Vibrio cholerae, ≥90% (SDS-PAGE), lyophilized powder
Quality Level
Assay
≥90% (SDS-PAGE)
form
lyophilized powder
composition
Protein, ~5% Lowry-TCA
solubility
H2O: 10 mg/mL
storage temp.
2-8°C
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General description
Cholera toxin and its A subunit are commonly used to study signal transduction mechanisms due to their impact on adenylate cyclase. Additionally, cholera toxin acts as an adjuvant by stimulating B lymphocytes and T helper cell type 2 responses by inhibiting interleukin-12 production. The non-toxic B subunit (CTB) attaches to cells by binding to ganglioside GM1, making it a useful label for microglial cells in neurological research. It has also proved to be an excellent tracer for axonal transport studies using immunohistochemical methods.
Application
Features and Benefits
Packaging
Physical form
Reconstitution
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 3
WGK
WGK 3
Certificates of Analysis (COA)
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